Share

Purcell, Robert H. us

List of all publications

Publishing since 1962 (Dinosaur)

    2010

  1. Journal Article Bukh J, Meuleman P, Tellier R, Engle RE, Feinstone SM, Eder G, Satterfield WC, Govindarajan S, Krawczynski K, Miller RH, Leroux-Roels G, Purcell RH. Challenge Pools of Hepatitis C Virus Genotypes 1-6 Prototype Strains: Replication Fitness and Pathogenicity in Chimpanzees and Human Liver-Chimeric Mouse Models.  J. Infect. Dis.  2010  Link to Challenge Pools of Hepatitis C Virus Genotypes 1-6 Prototype Strains: Replication Fitness and Pathogenicity in Chimpanzees and Human Liver-Chimeric Mouse Models.
  2. Journal Article Gottwein JM, Scheel TK, Callendret B, Li YP, Eccleston HB, Engle RE, Govindarajan S, Satterfield W, Purcell RH, Walker CM, Bukh J. Novel Infectious cDNA Clones of Hepatitis C Virus Genotype 3a (Strain S52) and 4a (Strain ED43): Genetic Analyses and In Vivo Pathogenesis Studies.  J. Virol.  2010  Link to Novel Infectious cDNA Clones of Hepatitis C Virus Genotype 3a (Strain S52) and 4a (Strain ED43): Genetic Analyses and In Vivo Pathogenesis Studies.
  3. Journal ArticleResearch Support, N.I.H., Intramural Takikawa S, Engle RE, Faulk KN, Emerson SU, Purcell RH, Bukh J. Molecular evolution of GB virus B hepatitis virus during acute resolving and persistent infections in experimentally infected tamarins.  J. Gen. Virol.  2010;91;Pt 3  Link to Molecular evolution of GB virus B hepatitis virus during acute resolving and persistent infections in experimentally infected tamarins.
  4. 2009

  5. Journal ArticleResearch Support, N.I.H., ExtramuralResearch Support, N.I.H., Intramural Blackard JT, Rouster SD, Nady S, Galal G, Marzuuk N, Rafaat MM, Daef E, El Din SS, Purcell RH, Emerson SU, Sherman KE, Shata MT. Genotypic characterization of symptomatic hepatitis E virus (HEV) infections in Egypt.  J. Clin. Virol.  2009;46;2  Link to Genotypic characterization of symptomatic hepatitis E virus (HEV) infections in Egypt.
  6. Journal ArticleResearch Support, N.I.H., ExtramuralResearch Support, N.I.H., Intramural Asabe S, Wieland SF, Chattopadhyay PK, Roederer M, Engle RE, Purcell RH, Chisari FV. The size of the viral inoculum contributes to the outcome of hepatitis B virus infection.  J. Virol.  2009;83;19  Link to The size of the viral inoculum contributes to the outcome of hepatitis B virus infection.
  7. Journal ArticleResearch Support, N.I.H., Intramural Russell RS, Kawaguchi K, Meunier JC, Takikawa S, Faulk K, Bukh J, Purcell RH, Emerson SU. Mutational analysis of the hepatitis C virus E1 glycoprotein in retroviral pseudoparticles and cell-culture-derived H77/JFH1 chimeric infectious virus particles.  J. Viral Hepat.  2009;16;9  Link to Mutational analysis of the hepatitis C virus E1 glycoprotein in retroviral pseudoparticles and cell-culture-derived H77/JFH1 chimeric infectious virus particles.
  8. Journal ArticleResearch Support, N.I.H., Intramural Chen Z, Moayeri M, Crown D, Emerson S, Gorshkova I, Schuck P, Leppla SH, Purcell RH. Novel chimpanzee/human monoclonal antibodies that neutralize anthrax lethal factor, and evidence for possible synergy with anti-protective antigen antibody.  Infect. Immun.  2009;77;9  Link to Novel chimpanzee/human monoclonal antibodies that neutralize anthrax lethal factor, and evidence for possible synergy with anti-protective antigen antibody.
  9. Journal ArticleResearch Support, N.I.H., Intramural Chen Z, Moayeri M, Zhao H, Crown D, Leppla SH, Purcell RH. Potent neutralization of anthrax edema toxin by a humanized monoclonal antibody that competes with calmodulin for edema factor binding.  Proc. Natl. Acad. Sci. U.S.A.  2009;106;32  Link to Potent neutralization of anthrax edema toxin by a humanized monoclonal antibody that competes with calmodulin for edema factor binding.
  10. Journal Article Kuniholm MH, Purcell RH, McQuillan GM, Engle RE, Wasley A, Nelson KE. Epidemiology of hepatitis E virus in the United States: results from the Third National Health and Nutrition Examination Survey, 1988-1994.  J. Infect. Dis.  2009;200;1  Link to Epidemiology of hepatitis E virus in the United States: results from the Third National Health and Nutrition Examination Survey, 1988-1994.
  11. Comparative StudyEvaluation StudiesJournal ArticleResearch Support, N.I.H., Extramural Tang S, Moayeri M, Chen Z, Harma H, Zhao J, Hu H, Purcell RH, Leppla SH, Hewlett IK. Detection of anthrax toxin by an ultrasensitive immunoassay using europium nanoparticles.  Clin. Vaccine Immunol.  2009;16;3  Link to Detection of anthrax toxin by an ultrasensitive immunoassay using europium nanoparticles.
  12. 2008

  13. Journal ArticleResearch Support, N.I.H., Intramural Christensen PB, Engle RE, Hjort C, Homburg KM, Vach W, Georgsen J, Purcell RH. Time trend of the prevalence of hepatitis E antibodies among farmers and blood donors: a potential zoonosis in Denmark.  Clin. Infect. Dis.  2008;47;8  Link to Time trend of the prevalence of hepatitis E antibodies among farmers and blood donors: a potential zoonosis in Denmark.
  14. Journal ArticleResearch Support, N.I.H., Intramural Meunier JC, Russell RS, Engle RE, Faulk KN, Purcell RH, Emerson SU. Apolipoprotein c1 association with hepatitis C virus.  J. Virol.  2008;82;19  Link to Apolipoprotein c1 association with hepatitis C virus.
  15. Journal ArticleResearch Support, N.I.H., ExtramuralResearch Support, N.I.H., Intramural Bukh J, Thimme R, Meunier JC, Faulk K, Spangenberg HC, Chang KM, Satterfield W, Chisari FV, Purcell RH. Previously infected chimpanzees are not consistently protected against reinfection or persistent infection after reexposure to the identical hepatitis C virus strain.  J. Virol.  2008;82;16  Link to Previously infected chimpanzees are not consistently protected against reinfection or persistent infection after reexposure to the identical hepatitis C virus strain.
  16. Journal ArticleResearch Support, N.I.H., Intramural Goncalvez AP, Chien CH, Tubthong K, Gorshkova I, Roll C, Donau O, Schuck P, Yoksan S, Wang SD, Purcell RH, Lai CJ. Humanized monoclonal antibodies derived from chimpanzee Fabs protect against Japanese encephalitis virus in vitro and in vivo.  J. Virol.  2008;82;14  Link to Humanized monoclonal antibodies derived from chimpanzee Fabs protect against Japanese encephalitis virus in vitro and in vivo.
  17. Journal ArticleResearch Support, N.I.H., Intramural Vanwolleghem T, Bukh J, Meuleman P, Desombere I, Meunier JC, Alter H, Purcell RH, Leroux-Roels G. Polyclonal immunoglobulins from a chronic hepatitis C virus patient protect human liver-chimeric mice from infection with a homologous hepatitis C virus strain.  Hepatology  2008;47;6  Link to Polyclonal immunoglobulins from a chronic hepatitis C virus patient protect human liver-chimeric mice from infection with a homologous hepatitis C virus strain.
  18. Journal ArticleResearch Support, N.I.H., Intramural Russell RS, Meunier JC, Takikawa S, Faulk K, Engle RE, Bukh J, Purcell RH, Emerson SU. Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus.  Proc. Natl. Acad. Sci. U.S.A.  2008;105;11  Link to Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus.
  19. Journal ArticleResearch Support, N.I.H., ExtramuralReview Purcell RH, Emerson SU. Hepatitis E: an emerging awareness of an old disease.  J. Hepatol.  2008;48;3  Link to Hepatitis E: an emerging awareness of an old disease.
  20. Journal ArticleResearch Support, N.I.H., Intramural Graff J, Zhou YH, Torian U, Nguyen H, St Claire M, Yu C, Purcell RH, Emerson SU. Mutations within potential glycosylation sites in the capsid protein of hepatitis E virus prevent the formation of infectious virus particles.  J. Virol.  2008;82;3  Link to Mutations within potential glycosylation sites in the capsid protein of hepatitis E virus prevent the formation of infectious virus particles.
  21. Journal ArticleResearch Support, N.I.H., Intramural Engle RE, Russell RS, Purcell RH, Bukh J. Development of a TaqMan assay for the six major genotypes of hepatitis C virus: comparison with commercial assays.  J. Med. Virol.  2008;80;1  Link to Development of a TaqMan assay for the six major genotypes of hepatitis C virus: comparison with commercial assays.
  22. Journal ArticleResearch Support, N.I.H., Intramural Bukh J, Engle RE, Govindarajan S, Purcell RH. Immunity against the GBV-B hepatitis virus in tamarins can prevent productive infection following rechallenge and is long-lived.  J. Med. Virol.  2008;80;1  Link to Immunity against the GBV-B hepatitis virus in tamarins can prevent productive infection following rechallenge and is long-lived.
  23. Journal ArticleResearch Support, N.I.H., Intramural Meunier JC, Russell RS, Goossens V, Priem S, Walter H, Depla E, Union A, Faulk KN, Bukh J, Emerson SU, Purcell RH. Isolation and characterization of broadly neutralizing human monoclonal antibodies to the e1 glycoprotein of hepatitis C virus.  J. Virol.  2008;82;2  Link to Isolation and characterization of broadly neutralizing human monoclonal antibodies to the e1 glycoprotein of hepatitis C virus.
  24. 2007

  25. Journal ArticleResearch Support, N.I.H., ExtramuralResearch Support, N.I.H., Intramural Shata MT, Barrett A, Shire NJ, Abdelwahab SF, Sobhy M, Daef E, El-Kamary SS, Hashem M, Engle RE, Purcell RH, Emerson SU, Strickland GT, Sherman KE. Characterization of hepatitis E-specific cell-mediated immune response using IFN-gamma ELISPOT assay.  J. Immunol. Methods  2007;328;1-2  Link to Characterization of hepatitis E-specific cell-mediated immune response using IFN-gamma ELISPOT assay.
  26. Journal ArticleResearch Support, N.I.H., ExtramuralResearch Support, N.I.H., Intramural Lai CJ, Goncalvez AP, Men R, Wernly C, Donau O, Engle RE, Purcell RH. Epitope determinants of a chimpanzee dengue virus type 4 (DENV-4)-neutralizing antibody and protection against DENV-4 challenge in mice and rhesus monkeys by passively transferred humanized antibody.  J. Virol.  2007;81;23  Link to Epitope determinants of a chimpanzee dengue virus type 4 (DENV-4)-neutralizing antibody and protection against DENV-4 challenge in mice and rhesus monkeys by passively transferred humanized antibody.
  27. Journal ArticleResearch Support, N.I.H., Extramural Easterbrook JD, Kaplan JB, Vanasco NB, Reeves WK, Purcell RH, Kosoy MY, Glass GE, Watson J, Klein SL. A survey of zoonotic pathogens carried by Norway rats in Baltimore, Maryland, USA.  Epidemiol. Infect.  2007;135;7  Link to A survey of zoonotic pathogens carried by Norway rats in Baltimore, Maryland, USA.
  28. Journal ArticleResearch Support, N.I.H., ExtramuralResearch Support, N.I.H., Intramural Sakai A, Takikawa S, Thimme R, Meunier JC, Spangenberg HC, Govindarajan S, Farci P, Emerson SU, Chisari FV, Purcell RH, Bukh J. In vivo study of the HC-TN strain of hepatitis C virus recovered from a patient with fulminant hepatitis: RNA transcripts of a molecular clone (pHC-TN) are infectious in chimpanzees but not in Huh7.5 cells.  J. Virol.  2007;81;13  Link to In vivo study of the HC-TN strain of hepatitis C virus recovered from a patient with fulminant hepatitis: RNA transcripts of a molecular clone (pHC-TN) are infectious in chimpanzees but not in Huh7.5 cells.
  29. Evaluation StudiesJournal ArticleResearch Support, N.I.H., Intramural Yu C, Zimmerman C, Stone R, Engle RE, Elkins W, Nardone GA, Emerson SU, Purcell RH. Using improved technology for filter paper-based blood collection to survey wild Sika deer for antibodies to hepatitis E virus.  J. Virol. Methods  2007;142;1-2  Link to Using improved technology for filter paper-based blood collection to survey wild Sika deer for antibodies to hepatitis E virus.
  30. Journal ArticleResearch Support, N.I.H., Intramural Goncalvez AP, Engle RE, St Claire M, Purcell RH, Lai CJ. Monoclonal antibody-mediated enhancement of dengue virus infection in vitro and in vivo and strategies for prevention.  Proc. Natl. Acad. Sci. U.S.A.  2007;104;22  Link to Monoclonal antibody-mediated enhancement of dengue virus infection in vitro and in vivo and strategies for prevention.
  31. 2006

  32. In VitroJournal ArticleResearch Support, N.I.H., Intramural Emerson SU, Nguyen H, Torian U, Purcell RH. ORF3 protein of hepatitis E virus is not required for replication, virion assembly, or infection of hepatoma cells in vitro.  J. Virol.  2006;80;21  Link to ORF3 protein of hepatitis E virus is not required for replication, virion assembly, or infection of hepatoma cells in vitro.
  33. Journal ArticleResearch Support, N.I.H., ExtramuralResearch Support, N.I.H., Intramural Murray JM, Purcell RH, Wieland SF. The half-life of hepatitis B virions.  Hepatology  2006;44;5  Link to The half-life of hepatitis B virions.
  34. Journal Article Hsia CC, Purcell RH, Farshid M, Lachenbruch PA, Yu MY. Quantification of hepatitis B virus genomes and infectivity in human serum samples.  Transfusion  2006;46;10  Link to Quantification of hepatitis B virus genomes and infectivity in human serum samples.
  35. CommentJournal Article Bukh J, Purcell RH. A milestone for hepatitis C virus research: a virus generated in cell culture is fully viable in vivo.  Proc. Natl. Acad. Sci. U.S.A.  2006;103;10  Link to A milestone for hepatitis C virus research: a virus generated in cell culture is fully viable in vivo.
  36. Journal ArticleResearch Support, N.I.H., Extramural Meky FA, Stoszek SK, Abdel-Hamid M, Selim S, Abdel-Wahab A, Mikhail N, El-Kafrawy S, El-Daly M, Abdel-Aziz F, Sharaf S, Mohamed MK, Engle RE, Emerson SU, Purcell RH, Fix AD, Strickland GT. Active surveillance for acute viral hepatitis in rural villages in the Nile Delta.  Clin. Infect. Dis.  2006;42;5  Link to Active surveillance for acute viral hepatitis in rural villages in the Nile Delta.
  37. Journal ArticleResearch Support, N.I.H., Intramural Emerson SU, Clemente-Casares P, Moiduddin N, Arankalle VA, Torian U, Purcell RH. Putative neutralization epitopes and broad cross-genotype neutralization of Hepatitis E virus confirmed by a quantitative cell-culture assay.  J. Gen. Virol.  2006;87;Pt 3  Link to Putative neutralization epitopes and broad cross-genotype neutralization of Hepatitis E virus confirmed by a quantitative cell-culture assay.
  38. Journal ArticleResearch Support, N.I.H., Intramural Takikawa S, Engle RE, Emerson SU, Purcell RH, St Claire M, Bukh J. Functional analyses of GB virus B p13 protein: development of a recombinant GB virus B hepatitis virus with a p7 protein.  Proc. Natl. Acad. Sci. U.S.A.  2006;103;9  Link to Functional analyses of GB virus B p13 protein: development of a recombinant GB virus B hepatitis virus with a p7 protein.
  39. Journal Article Payette PJ, Ma X, Weeratna RD, McCluskie MJ, Shapiro M, Engle RE, Davis HL, Purcell RH. Testing of CpG-optimized protein and DNA vaccines against the hepatitis B virus in chimpanzees for immunogenicity and protection from challenge.  Intervirology  2006;49;3  Link to Testing of CpG-optimized protein and DNA vaccines against the hepatitis B virus in chimpanzees for immunogenicity and protection from challenge.
  40. 2005

  41. Journal ArticleResearch Support, N.I.H., Extramural Murray JM, Wieland SF, Purcell RH, Chisari FV. Dynamics of hepatitis B virus clearance in chimpanzees.  Proc. Natl. Acad. Sci. U.S.A.  2005;102;49  Link to Dynamics of hepatitis B virus clearance in chimpanzees.
  42. Journal Article Schofield DJ, Bartosch B, Shimizu YK, Allander T, Alter HJ, Emerson SU, Cosset FL, Purcell RH. Human monoclonal antibodies that react with the E2 glycoprotein of hepatitis C virus and possess neutralizing activity.  Hepatology  2005;42;5  Link to Human monoclonal antibodies that react with the E2 glycoprotein of hepatitis C virus and possess neutralizing activity.
  43. Comparative StudyJournal ArticleResearch Support, N.I.H., IntramuralResearch Support, U.S. Gov't, P.H.S. Emerson SU, Arankalle VA, Purcell RH. Thermal stability of hepatitis E virus.  J. Infect. Dis.  2005;192;5  Link to Thermal stability of hepatitis E virus.
  44. Journal Article Graff J, Nguyen H, Yu C, Elkins WR, St Claire M, Purcell RH, Emerson SU. The open reading frame 3 gene of hepatitis E virus contains a cis-reactive element and encodes a protein required for infection of macaques.  J. Virol.  2005;79;11  Link to The open reading frame 3 gene of hepatitis E virus contains a cis-reactive element and encodes a protein required for infection of macaques.
  45. Journal Article Zhou YH, Purcell RH, Emerson SU. A truncated ORF2 protein contains the most immunogenic site on ORF2: antibody responses to non-vaccine sequences following challenge of vaccinated and non-vaccinated macaques with hepatitis E virus.  Vaccine  2005;23;24  Link to A truncated ORF2 protein contains the most immunogenic site on ORF2: antibody responses to non-vaccine sequences following challenge of vaccinated and non-vaccinated macaques with hepatitis E virus.
  46. Journal Article Meunier JC, Engle RE, Faulk K, Zhao M, Bartosch B, Alter H, Emerson SU, Cosset FL, Purcell RH, Bukh J. Evidence for cross-genotype neutralization of hepatitis C virus pseudo-particles and enhancement of infectivity by apolipoprotein C1.  Proc. Natl. Acad. Sci. U.S.A.  2005;102;12  Link to Evidence for cross-genotype neutralization of hepatitis C virus pseudo-particles and enhancement of infectivity by apolipoprotein C1.
  47. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Graff J, Nguyen H, Kasorndorkbua C, Halbur PG, St Claire M, Purcell RH, Emerson SU. In vitro and in vivo mutational analysis of the 3'-terminal regions of hepatitis e virus genomes and replicons.  J. Virol.  2005;79;2  Link to In vitro and in vivo mutational analysis of the 3'-terminal regions of hepatitis e virus genomes and replicons.
  48. 2004

  49. Journal Article Emerson SU, Purcell RH. Running like water--the omnipresence of hepatitis E.  N. Engl. J. Med.  2004;351;23  Link to Running like water--the omnipresence of hepatitis E.
  50. Journal Article Goncalvez AP, Purcell RH, Lai CJ. Epitope determinants of a chimpanzee Fab antibody that efficiently cross-neutralizes dengue type 1 and type 2 viruses map to inside and in close proximity to fusion loop of the dengue type 2 virus envelope glycoprotein.  J. Virol.  2004;78;23  Link to Epitope determinants of a chimpanzee Fab antibody that efficiently cross-neutralizes dengue type 1 and type 2 viruses map to inside and in close proximity to fusion loop of the dengue type 2 virus envelope glycoprotein.
  51. Journal Article Goncalvez AP, Men R, Wernly C, Purcell RH, Lai CJ. Chimpanzee Fab fragments and a derived humanized immunoglobulin G1 antibody that efficiently cross-neutralize dengue type 1 and type 2 viruses.  J. Virol.  2004;78;23  Link to Chimpanzee Fab fragments and a derived humanized immunoglobulin G1 antibody that efficiently cross-neutralize dengue type 1 and type 2 viruses.
  52. Journal Article Zhou YH, Purcell RH, Emerson SU. An ELISA for putative neutralizing antibodies to hepatitis E virus detects antibodies to genotypes 1, 2, 3, and 4.  Vaccine  2004;22;20  Link to An ELISA for putative neutralizing antibodies to hepatitis E virus detects antibodies to genotypes 1, 2, 3, and 4.
  53. Clinical TrialJournal ArticleRandomized Controlled Trial Farci P, Roskams T, Chessa L, Peddis G, Mazzoleni AP, Scioscia R, Serra G, Lai ME, Loy M, Caruso L, Desmet V, Purcell RH, Balestrieri A. Long-term benefit of interferon alpha therapy of chronic hepatitis D: regression of advanced hepatic fibrosis.  Gastroenterology  2004;126;7  Link to Long-term benefit of interferon alpha therapy of chronic hepatitis D: regression of advanced hepatic fibrosis.
  54. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Huang FF, Sun ZF, Emerson SU, Purcell RH, Shivaprasad HL, Pierson FW, Toth TE, Meng XJ. Determination and analysis of the complete genomic sequence of avian hepatitis E virus (avian HEV) and attempts to infect rhesus monkeys with avian HEV.  J. Gen. Virol.  2004;85;Pt 6  Link to Determination and analysis of the complete genomic sequence of avian hepatitis E virus (avian HEV) and attempts to infect rhesus monkeys with avian HEV.
  55. Journal Article Yu MY, Bartosch B, Zhang P, Guo ZP, Renzi PM, Shen LM, Granier C, Feinstone SM, Cosset FL, Purcell RH. Neutralizing antibodies to hepatitis C virus (HCV) in immune globulins derived from anti-HCV-positive plasma.  Proc. Natl. Acad. Sci. U.S.A.  2004;101;20  Link to Neutralizing antibodies to hepatitis C virus (HCV) in immune globulins derived from anti-HCV-positive plasma.
  56. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Emerson SU, Nguyen H, Graff J, Stephany DA, Brockington A, Purcell RH. In vitro replication of hepatitis E virus (HEV) genomes and of an HEV replicon expressing green fluorescent protein.  J. Virol.  2004;78;9  Link to In vitro replication of hepatitis E virus (HEV) genomes and of an HEV replicon expressing green fluorescent protein.
  57. Journal Article Men R, Yamashiro T, Goncalvez AP, Wernly C, Schofield DJ, Emerson SU, Purcell RH, Lai CJ. Identification of chimpanzee Fab fragments by repertoire cloning and production of a full-length humanized immunoglobulin G1 antibody that is highly efficient for neutralization of dengue type 4 virus.  J. Virol.  2004;78;9  Link to Identification of chimpanzee Fab fragments by repertoire cloning and production of a full-length humanized immunoglobulin G1 antibody that is highly efficient for neutralization of dengue type 4 virus.
  58. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Wieland S, Thimme R, Purcell RH, Chisari FV. Genomic analysis of the host response to hepatitis B virus infection.  Proc. Natl. Acad. Sci. U.S.A.  2004;101;17  Link to Genomic analysis of the host response to hepatitis B virus infection.
  59. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Wieland SF, Spangenberg HC, Thimme R, Purcell RH, Chisari FV. Expansion and contraction of the hepatitis B virus transcriptional template in infected chimpanzees.  Proc. Natl. Acad. Sci. U.S.A.  2004;101;7  Link to Expansion and contraction of the hepatitis B virus transcriptional template in infected chimpanzees.
  60. 2003

  61. Journal Article Schofield DJ, Purcell RH, Nguyen HT, Emerson SU. Monoclonal antibodies that neutralize HEV recognize an antigenic site at the carboxyterminus of an ORF2 protein vaccine.  Vaccine  2003;22;2  Link to Monoclonal antibodies that neutralize HEV recognize an antigenic site at the carboxyterminus of an ORF2 protein vaccine.
  62. In VitroJournal Article Bartosch B, Bukh J, Meunier JC, Granier C, Engle RE, Blackwelder WC, Emerson SU, Cosset FL, Purcell RH. In vitro assay for neutralizing antibody to hepatitis C virus: evidence for broadly conserved neutralization epitopes.  Proc. Natl. Acad. Sci. U.S.A.  2003;100;24  Link to In vitro assay for neutralizing antibody to hepatitis C virus: evidence for broadly conserved neutralization epitopes.
  63. Journal Article Sakai A, Claire MS, Faulk K, Govindarajan S, Emerson SU, Purcell RH, Bukh J. The p7 polypeptide of hepatitis C virus is critical for infectivity and contains functionally important genotype-specific sequences.  Proc. Natl. Acad. Sci. U.S.A.  2003;100;20  Link to The p7 polypeptide of hepatitis C virus is critical for infectivity and contains functionally important genotype-specific sequences.
  64. Journal Article Yu C, Engle RE, Bryan JP, Emerson SU, Purcell RH. Detection of immunoglobulin M antibodies to hepatitis E virus by class capture enzyme immunoassay.  Clin. Diagn. Lab. Immunol.  2003;10;4  Link to Detection of immunoglobulin M antibodies to hepatitis E virus by class capture enzyme immunoassay.
  65. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Purcell RH, Nguyen H, Shapiro M, Engle RE, Govindarajan S, Blackwelder WC, Wong DC, Prieels JP, Emerson SU. Pre-clinical immunogenicity and efficacy trial of a recombinant hepatitis E vaccine.  Vaccine  2003;21;19-20  Link to Pre-clinical immunogenicity and efficacy trial of a recombinant hepatitis E vaccine.
  66. Journal ArticleReview Emerson SU, Purcell RH. Hepatitis E virus.  Rev. Med. Virol.  2003;13;3  Link to Hepatitis E virus.
  67. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Thimme R, Wieland S, Steiger C, Ghrayeb J, Reimann KA, Purcell RH, Chisari FV. CD8(+) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection.  J. Virol.  2003;77;1  Link to CD8(+) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection.
  68. 2002

  69. Journal Article Smith HM, Reporter R, Rood MP, Linscott AJ, Mascola LM, Hogrefe W, Purcell RH. Prevalence study of antibody to ratborne pathogens and other agents among patients using a free clinic in downtown Los Angeles.  J. Infect. Dis.  2002;186;11  Link to Prevalence study of antibody to ratborne pathogens and other agents among patients using a free clinic in downtown Los Angeles.
  70. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Thimme R, Bukh J, Spangenberg HC, Wieland S, Pemberton J, Steiger C, Govindarajan S, Purcell RH, Chisari FV. Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease.  Proc. Natl. Acad. Sci. U.S.A.  2002;99;24  Link to Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease.
  71. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Su AI, Pezacki JP, Wodicka L, Brideau AD, Supekova L, Thimme R, Wieland S, Bukh J, Purcell RH, Schultz PG, Chisari FV. Genomic analysis of the host response to hepatitis C virus infection.  Proc. Natl. Acad. Sci. U.S.A.  2002;99;24  Link to Genomic analysis of the host response to hepatitis C virus infection.
  72. Journal ArticleReview Forns X, Bukh J, Purcell RH. The challenge of developing a vaccine against hepatitis C virus.  J. Hepatol.  2002;37;5  Link to The challenge of developing a vaccine against hepatitis C virus.
  73. Journal Article Ma X, Forns X, Gutierrez R, Mushahwar IK, Wu T, Payette PJ, Bukh J, Purcell RH, Davis HL. DNA-based vaccination against hepatitis C virus (HCV): effect of expressing different forms of HCV E2 protein and use of CpG-optimized vectors in mice.  Vaccine  2002;20;27-28  Link to DNA-based vaccination against hepatitis C virus (HCV): effect of expressing different forms of HCV E2 protein and use of CpG-optimized vectors in mice.
  74. Journal Article Zhang M, Emerson SU, Nguyen H, Engle R, Govindarajan S, Blackwelder WC, Gerin J, Purcell RH. Recombinant vaccine against hepatitis E: duration of protective immunity in rhesus macaques.  Vaccine  2002;20;27-28  Link to Recombinant vaccine against hepatitis E: duration of protective immunity in rhesus macaques.
  75. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Emerson SU, Huang YK, Nguyen H, Brockington A, Govindarajan S, St Claire M, Shapiro M, Purcell RH. Identification of VP1/2A and 2C as virulence genes of hepatitis A virus and demonstration of genetic instability of 2C.  J. Virol.  2002;76;17  Link to Identification of VP1/2A and 2C as virulence genes of hepatitis A virus and demonstration of genetic instability of 2C.
  76. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Purcell RH, Wong DC, Shapiro M. Relative infectivity of hepatitis A virus by the oral and intravenous routes in 2 species of nonhuman primates.  J. Infect. Dis.  2002;185;11  Link to Relative infectivity of hepatitis A virus by the oral and intravenous routes in 2 species of nonhuman primates.
  77. Journal Article Farci P, Strazzera R, Alter HJ, Farci S, Degioannis D, Coiana A, Peddis G, Usai F, Serra G, Chessa L, Diaz G, Balestrieri A, Purcell RH. Early changes in hepatitis C viral quasispecies during interferon therapy predict the therapeutic outcome.  Proc. Natl. Acad. Sci. U.S.A.  2002;99;5  Link to Early changes in hepatitis C viral quasispecies during interferon therapy predict the therapeutic outcome.
  78. Journal Article Schofield DJ, Satterfield W, Emerson SU, Purcell RH. Four chimpanzee monoclonal antibodies isolated by phage display neutralize hepatitis a virus.  Virology  2002;292;1  Link to Four chimpanzee monoclonal antibodies isolated by phage display neutralize hepatitis a virus.
  79. Journal Article Christensen PB, Engle RE, Jacobsen SE, Krarup HB, Georgsen J, Purcell RH. High prevalence of hepatitis E antibodies among Danish prisoners and drug users.  J. Med. Virol.  2002;66;1  Link to High prevalence of hepatitis E antibodies among Danish prisoners and drug users.
  80. 2001

  81. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Emerson SU, Zhang M, Meng XJ, Nguyen H, St Claire M, Govindarajan S, Huang YK, Purcell RH. Recombinant hepatitis E virus genomes infectious for primates: importance of capping and discovery of a cis-reactive element.  Proc. Natl. Acad. Sci. U.S.A.  2001;98;26  Link to Recombinant hepatitis E virus genomes infectious for primates: importance of capping and discovery of a cis-reactive element.
  82. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Zhang M, Emerson SU, Nguyen H, Engle RE, Govindarajan S, Gerin JL, Purcell RH. Immunogenicity and protective efficacy of a vaccine prepared from 53 kDa truncated hepatitis E virus capsid protein expressed in insect cells.  Vaccine  2001;20;5-6  Link to Immunogenicity and protective efficacy of a vaccine prepared from 53 kDa truncated hepatitis E virus capsid protein expressed in insect cells.
  83. Comparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S. Bukh J, Apgar CL, Govindarajan S, Purcell RH. Host range studies of GB virus-B hepatitis agent, the closest relative of hepatitis C virus, in New World monkeys and chimpanzees.  J. Med. Virol.  2001;65;4  Link to Host range studies of GB virus-B hepatitis agent, the closest relative of hepatitis C virus, in New World monkeys and chimpanzees.
  84. Comparative StudyJournal Article Zhang M, Purcell RH, Emerson SU. Identification of the 5' terminal sequence of the SAR-55 and MEX-14 strains of hepatitis E virus and confirmation that the genome is capped.  J. Med. Virol.  2001;65;2  Link to Identification of the 5' terminal sequence of the SAR-55 and MEX-14 strains of hepatitis E virus and confirmation that the genome is capped.
  85. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Allander T, Emerson SU, Engle RE, Purcell RH, Bukh J. A virus discovery method incorporating DNase treatment and its application to the identification of two bovine parvovirus species.  Proc. Natl. Acad. Sci. U.S.A.  2001;98;20  Link to A virus discovery method incorporating DNase treatment and its application to the identification of two bovine parvovirus species.
  86. Journal Article Nam JH, Bukh J, Purcell RH, Emerson SU. High-level expression of hepatitis C virus (HCV) structural proteins by a chimeric HCV/BVDV genome propagated as a BVDV pseudotype.  J. Virol. Methods  2001;97;1-2  Link to High-level expression of hepatitis C virus (HCV) structural proteins by a chimeric HCV/BVDV genome propagated as a BVDV pseudotype.
  87. Case ReportsJournal Article Kabrane-Lazizi Y, Zhang M, Purcell RH, Miller KD, Davey RT, Emerson SU. Acute hepatitis caused by a novel strain of hepatitis E virus most closely related to United States strains.  J. Gen. Virol.  2001;82;Pt 7  Link to Acute hepatitis caused by a novel strain of hepatitis E virus most closely related to United States strains.
  88. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Bukh J, Apgar CL, Govindarajan S, Emerson SU, Purcell RH. Failure to infect rhesus monkeys with hepatitis C virus strains of genotypes 1a, 2a or 3a.  J. Viral Hepat.  2001;8;3  Link to Failure to infect rhesus monkeys with hepatitis C virus strains of genotypes 1a, 2a or 3a.
  89. Journal Article Kabrane-Lazizi Y, Emerson SU, Herzog C, Purcell RH. Detection of antibodies to HAV 3C proteinase in experimentally infected chimpanzees and in naturally infected children.  Vaccine  2001;19;20-22  Link to Detection of antibodies to HAV 3C proteinase in experimentally infected chimpanzees and in naturally infected children.
  90. Journal ArticleReview Bukh J, Forns X, Emerson SU, Purcell RH. Studies of hepatitis C virus in chimpanzees and their importance for vaccine development.  Intervirology  2001;44;2-3  Link to Studies of hepatitis C virus in chimpanzees and their importance for vaccine development.
  91. BiographyClassical ArticleHistorical ArticleJournal Article Feinstone SM, Kapikian AZ, Purcell RH, Alter HJ, Holland PV. Transfusion-associated hepatitis not due to viral hepatitis type A or B. 1975.  Rev. Med. Virol.  2001;11;1  Link to Transfusion-associated hepatitis not due to viral hepatitis type A or B. 1975.
  92. 2000

  93. Comparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S. Allander T, Forns X, Emerson SU, Purcell RH, Bukh J. Hepatitis C virus envelope protein E2 binds to CD81 of tamarins.  Virology  2000;277;2  Link to Hepatitis C virus envelope protein E2 binds to CD81 of tamarins.
  94. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Forns X, Thimme R, Govindarajan S, Emerson SU, Purcell RH, Chisari FV, Bukh J. Hepatitis C virus lacking the hypervariable region 1 of the second envelope protein is infectious and causes acute resolving or persistent infection in chimpanzees.  Proc. Natl. Acad. Sci. U.S.A.  2000;97;24  Link to Hepatitis C virus lacking the hypervariable region 1 of the second envelope protein is infectious and causes acute resolving or persistent infection in chimpanzees.
  95. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Forns X, Payette PJ, Ma X, Satterfield W, Eder G, Mushahwar IK, Govindarajan S, Davis HL, Emerson SU, Purcell RH, Bukh J. Vaccination of chimpanzees with plasmid DNA encoding the hepatitis C virus (HCV) envelope E2 protein modified the infection after challenge with homologous monoclonal HCV.  Hepatology  2000;32;3  Link to Vaccination of chimpanzees with plasmid DNA encoding the hepatitis C virus (HCV) envelope E2 protein modified the infection after challenge with homologous monoclonal HCV.
  96. CommentLetter Purcell RH. Hepatitis B virus mutants and efficacy of vaccination.  Lancet  2000;356;9231  Link to Hepatitis B virus mutants and efficacy of vaccination.
  97. Journal Article Schofield DJ, Glamann J, Emerson SU, Purcell RH. Identification by phage display and characterization of two neutralizing chimpanzee monoclonal antibodies to the hepatitis E virus capsid protein.  J. Virol.  2000;74;12  Link to Identification by phage display and characterization of two neutralizing chimpanzee monoclonal antibodies to the hepatitis E virus capsid protein.
  98. Comparative StudyJournal Article Farci P, Shimoda A, Coiana A, Diaz G, Peddis G, Melpolder JC, Strazzera A, Chien DY, Munoz SJ, Balestrieri A, Purcell RH, Alter HJ. The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies.  Science  2000;288;5464  Link to The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies.
  99. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Romeo R, Hegerich P, Emerson SU, Colombo M, Purcell RH, Bukh J. High prevalence of TT virus (TTV) in naive chimpanzees and in hepatitis C virus-infected humans: frequent mixed infections and identification of new TTV genotypes in chimpanzees.  J. Gen. Virol.  2000;81;Pt 4  Link to High prevalence of TT virus (TTV) in naive chimpanzees and in hepatitis C virus-infected humans: frequent mixed infections and identification of new TTV genotypes in chimpanzees.
  100. Journal Article Hu X, Margolis HS, Purcell RH, Ebert J, Robertson BH. Identification of hepatitis B virus indigenous to chimpanzees.  Proc. Natl. Acad. Sci. U.S.A.  2000;97;4  Link to Identification of hepatitis B virus indigenous to chimpanzees.
  101. CommentLetter Purcell RH, Emerson SU. Hepatitis E virus infection.  Lancet  2000;355;9203  Link to Hepatitis E virus infection.
  102. Comparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S. Hartmann G, Weeratna RD, Ballas ZK, Payette P, Blackwell S, Suparto I, Rasmussen WL, Waldschmidt M, Sajuthi D, Purcell RH, Davis HL, Krieg AM. Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo.  J. Immunol.  2000;164;3  Link to Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo.
  103. Journal ArticleReview Farci P, Purcell RH. Clinical significance of hepatitis C virus genotypes and quasispecies.  Semin. Liver Dis.  2000;20;1  Link to Clinical significance of hepatitis C virus genotypes and quasispecies.
  104. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Cote PJ, Korba BE, Miller RH, Jacob JR, Baldwin BH, Hornbuckle WE, Purcell RH, Tennant BC, Gerin JL. Effects of age and viral determinants on chronicity as an outcome of experimental woodchuck hepatitis virus infection.  Hepatology  2000;31;1  Link to Effects of age and viral determinants on chronicity as an outcome of experimental woodchuck hepatitis virus infection.
  105. 1999

  106. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Forns X, Hegerich P, Darnell A, Emerson SU, Purcell RH, Bukh J. High prevalence of TT virus (TTV) infection in patients on maintenance hemodialysis: frequent mixed infections with different genotypes and lack of evidence of associated liver disease.  J. Med. Virol.  1999;59;3  Link to High prevalence of TT virus (TTV) infection in patients on maintenance hemodialysis: frequent mixed infections with different genotypes and lack of evidence of associated liver disease.
  107. Journal Article Meng XJ, Dea S, Engle RE, Friendship R, Lyoo YS, Sirinarumitr T, Urairong K, Wang D, Wong D, Yoo D, Zhang Y, Purcell RH, Emerson SU. Prevalence of antibodies to the hepatitis E virus in pigs from countries where hepatitis E is common or is rare in the human population.  J. Med. Virol.  1999;59;3  Link to Prevalence of antibodies to the hepatitis E virus in pigs from countries where hepatitis E is common or is rare in the human population.
  108. Journal Article Kabrane-Lazizi Y, Meng XJ, Purcell RH, Emerson SU. Evidence that the genomic RNA of hepatitis E virus is capped.  J. Virol.  1999;73;10  Link to Evidence that the genomic RNA of hepatitis E virus is capped.
  109. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Yanagi M, Purcell RH, Emerson SU, Bukh J. Hepatitis C virus: an infectious molecular clone of a second major genotype (2a) and lack of viability of intertypic 1a and 2a chimeras.  Virology  1999;262;1  Link to Hepatitis C virus: an infectious molecular clone of a second major genotype (2a) and lack of viability of intertypic 1a and 2a chimeras.
  110. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Ogata N, Cote PJ, Zanetti AR, Miller RH, Shapiro M, Gerin J, Purcell RH. Licensed recombinant hepatitis B vaccines protect chimpanzees against infection with the prototype surface gene mutant of hepatitis B virus.  Hepatology  1999;30;3  Link to Licensed recombinant hepatitis B vaccines protect chimpanzees against infection with the prototype surface gene mutant of hepatitis B virus.
  111. Journal Article Arankalle VA, Paranjape S, Emerson SU, Purcell RH, Walimbe AM. Phylogenetic analysis of hepatitis E virus isolates from India (1976-1993).  J. Gen. Virol.  1999;80 ( Pt 7)  Link to Phylogenetic analysis of hepatitis E virus isolates from India (1976-1993).
  112. Comparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S. Forns X, Emerson SU, Tobin GJ, Mushahwar IK, Purcell RH, Bukh J. DNA immunization of mice and macaques with plasmids encoding hepatitis C virus envelope E2 protein expressed intracellularly and on the cell surface.  Vaccine  1999;17;15-16  Link to DNA immunization of mice and macaques with plasmids encoding hepatitis C virus envelope E2 protein expressed intracellularly and on the cell surface.
  113. Journal Article Farci P, Munoz SJ, Shimoda A, Govindarajan S, Wong DC, Coiana A, Peddis G, Rubin R, Purcell RH. Experimental transmission of hepatitis C virus-associated fulminant hepatitis to a chimpanzee.  J. Infect. Dis.  1999;179;4  Link to Experimental transmission of hepatitis C virus-associated fulminant hepatitis to a chimpanzee.
  114. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Yanagi M, St Claire M, Emerson SU, Purcell RH, Bukh J. In vivo analysis of the 3' untranslated region of the hepatitis C virus after in vitro mutagenesis of an infectious cDNA clone.  Proc. Natl. Acad. Sci. U.S.A.  1999;96;5  Link to In vivo analysis of the 3' untranslated region of the hepatitis C virus after in vitro mutagenesis of an infectious cDNA clone.
  115. Journal Article Funkhouser AW, Schultz DE, Lemon SM, Purcell RH, Emerson SU. Hepatitis A virus translation is rate-limiting for virus replication in MRC-5 cells.  Virology  1999;254;2  Link to Hepatitis A virus translation is rate-limiting for virus replication in MRC-5 cells.
  116. 1998

  117. Journal Article Meng XJ, Halbur PG, Shapiro MS, Govindarajan S, Bruna JD, Mushahwar IK, Purcell RH, Emerson SU. Genetic and experimental evidence for cross-species infection by swine hepatitis E virus.  J. Virol.  1998;72;12  Link to Genetic and experimental evidence for cross-species infection by swine hepatitis E virus.
  118. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Raychaudhuri G, Govindarajan S, Shapiro M, Purcell RH, Emerson SU. Utilization of chimeras between human (HM-175) and simian (AGM-27) strains of hepatitis A virus to study the molecular basis of virulence.  J. Virol.  1998;72;9  Link to Utilization of chimeras between human (HM-175) and simian (AGM-27) strains of hepatitis A virus to study the molecular basis of virulence.
  119. Comparative StudyJournal Article Shimoda A, Sugata F, Chen HS, Miller RH, Purcell RH. Evidence for a bidirectional promoter complex within the X gene of woodchuck hepatitis virus.  Virus Res.  1998;56;1  Link to Evidence for a bidirectional promoter complex within the X gene of woodchuck hepatitis virus.
  120. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Smedile A, Casey JL, Cote PJ, Durazzo M, Lavezzo B, Purcell RH, Rizzetto M, Gerin JL. Hepatitis D viremia following orthotopic liver transplantation involves a typical HDV virion with a hepatitis B surface antigen envelope.  Hepatology  1998;27;6  Link to Hepatitis D viremia following orthotopic liver transplantation involves a typical HDV virion with a hepatitis B surface antigen envelope.
  121. Journal Article Shimizu YK, Igarashi H, Kiyohara T, Shapiro M, Wong DC, Purcell RH, Yoshikura H. Infection of a chimpanzee with hepatitis C virus grown in cell culture.  J. Gen. Virol.  1998;79 ( Pt 6)  Link to Infection of a chimpanzee with hepatitis C virus grown in cell culture.
  122. Comparative StudyJournal Article Ghabrah TM, Tsarev S, Yarbough PO, Emerson SU, Strickland GT, Purcell RH. Comparison of tests for antibody to hepatitis E virus.  J. Med. Virol.  1998;55;2  Link to Comparison of tests for antibody to hepatitis E virus.
  123. Journal Article Arankalle VA, Chadha MS, Dama BM, Tsarev SA, Purcell RH, Banerjee K. Role of immune serum globulins in pregnant women during an epidemic of hepatitis E.  J. Viral Hepat.  1998;5;3  Link to Role of immune serum globulins in pregnant women during an epidemic of hepatitis E.
  124. Journal Article Yu M, Emerson SU, Cote P, Shapiro M, Purcell RH. The GDPAL region of the pre-S1 envelope protein is important for morphogenesis of woodchuck hepatitis virus.  Hepatology  1998;27;5  Link to The GDPAL region of the pre-S1 envelope protein is important for morphogenesis of woodchuck hepatitis virus.
  125. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Yanagi M, St Claire M, Shapiro M, Emerson SU, Purcell RH, Bukh J. Transcripts of a chimeric cDNA clone of hepatitis C virus genotype 1b are infectious in vivo.  Virology  1998;244;1  Link to Transcripts of a chimeric cDNA clone of hepatitis C virus genotype 1b are infectious in vivo.
  126. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Bukh J, Kim JP, Govindarajan S, Apgar CL, Foung SK, Wages J, Yun AJ, Shapiro M, Emerson SU, Purcell RH. Experimental infection of chimpanzees with hepatitis G virus and genetic analysis of the virus.  J. Infect. Dis.  1998;177;4  Link to Experimental infection of chimpanzees with hepatitis G virus and genetic analysis of the virus.
  127. Journal Article Mast EE, Alter MJ, Holland PV, Purcell RH. Evaluation of assays for antibody to hepatitis E virus by a serum panel. Hepatitis E Virus Antibody Serum Panel Evaluation Group.  Hepatology  1998;27;3  Link to Evaluation of assays for antibody to hepatitis E virus by a serum panel. Hepatitis E Virus Antibody Serum Panel Evaluation Group.
  128. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Chen HS, Miller RH, Hornbuckle WE, Tennant BC, Cote PJ, Gerin JL, Purcell RH. Titration of recombinant woodchuck hepatitis virus DNA in adult woodchucks.  J. Med. Virol.  1998;54;2  Link to Titration of recombinant woodchuck hepatitis virus DNA in adult woodchucks.
  129. Comparative StudyJournal Article Meng XJ, Halbur PG, Haynes JS, Tsareva TS, Bruna JD, Royer RL, Purcell RH, Emerson SU. Experimental infection of pigs with the newly identified swine hepatitis E virus (swine HEV), but not with human strains of HEV.  Arch. Virol.  1998;143;7  Link to Experimental infection of pigs with the newly identified swine hepatitis E virus (swine HEV), but not with human strains of HEV.
  130. 1997

  131. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Forns X, Bukh J, Purcell RH, Emerson SU. How Escherichia coli can bias the results of molecular cloning: preferential selection of defective genomes of hepatitis C virus during the cloning procedure.  Proc. Natl. Acad. Sci. U.S.A.  1997;94;25  Link to How Escherichia coli can bias the results of molecular cloning: preferential selection of defective genomes of hepatitis C virus during the cloning procedure.
  132. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Tsarev SA, Tsareva TS, Emerson SU, Govindarajan S, Shapiro M, Gerin JL, Purcell RH. Recombinant vaccine against hepatitis E: dose response and protection against heterologous challenge.  Vaccine  1997;15;17-18  Link to Recombinant vaccine against hepatitis E: dose response and protection against heterologous challenge.
  133. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Chatterjee R, Tsarev S, Pillot J, Coursaget P, Emerson SU, Purcell RH. African strains of hepatitis E virus that are distinct from Asian strains.  J. Med. Virol.  1997;53;2  Link to African strains of hepatitis E virus that are distinct from Asian strains.
  134. Journal Article Meng XJ, Purcell RH, Halbur PG, Lehman JR, Webb DM, Tsareva TS, Haynes JS, Thacker BJ, Emerson SU. A novel virus in swine is closely related to the human hepatitis E virus.  Proc. Natl. Acad. Sci. U.S.A.  1997;94;18  Link to A novel virus in swine is closely related to the human hepatitis E virus.
  135. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Villano SA, Nelson KE, Vlahov D, Purcell RH, Saah AJ, Thomas DL. Hepatitis A among homosexual men and injection drug users: more evidence for vaccination.  Clin. Infect. Dis.  1997;25;3  Link to Hepatitis A among homosexual men and injection drug users: more evidence for vaccination.
  136. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Stewart DR, Morris TS, Purcell RH, Emerson SU. Detection of antibodies to the nonstructural 3C proteinase of hepatitis A virus.  J. Infect. Dis.  1997;176;3  Link to Detection of antibodies to the nonstructural 3C proteinase of hepatitis A virus.
  137. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Yanagi M, Purcell RH, Emerson SU, Bukh J. Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee.  Proc. Natl. Acad. Sci. U.S.A.  1997;94;16  Link to Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee.
  138. Journal Article Shimizu YK, Igarashi H, Kanematu T, Fujiwara K, Wong DC, Purcell RH, Yoshikura H. Sequence analysis of the hepatitis C virus genome recovered from serum, liver, and peripheral blood mononuclear cells of infected chimpanzees.  J. Virol.  1997;71;8  Link to Sequence analysis of the hepatitis C virus genome recovered from serum, liver, and peripheral blood mononuclear cells of infected chimpanzees.
  139. Case ReportsJournal ArticleResearch Support, U.S. Gov't, P.H.S. Ogata N, Zanetti AR, Yu M, Miller RH, Purcell RH. Infectivity and pathogenicity in chimpanzees of a surface gene mutant of hepatitis B virus that emerged in a vaccinated infant.  J. Infect. Dis.  1997;175;3  Link to Infectivity and pathogenicity in chimpanzees of a surface gene mutant of hepatitis B virus that emerged in a vaccinated infant.
  140. Journal Article Chengalvala MV, Bhat BM, Bhat RA, Dheer SK, Lubeck MD, Purcell RH, Murthy KK. Replication and immunogenicity of Ad7-, Ad4-, and Ad5-hepatitis B virus surface antigen recombinants, with or without a portion of E3 region, in chimpanzees.  Vaccine  1997;15;3  Link to Replication and immunogenicity of Ad7-, Ad4-, and Ad5-hepatitis B virus surface antigen recombinants, with or without a portion of E3 region, in chimpanzees.
  141. Journal ArticleReview Farci P, Bukh J, Purcell RH. The quasispecies of hepatitis C virus and the host immune response.  Springer Semin. Immunopathol.  1997;19;1  Link to The quasispecies of hepatitis C virus and the host immune response.
  142. 1996

  143. Journal Article Farci P, Shimoda A, Wong D, Cabezon T, De Gioannis D, Strazzera A, Shimizu Y, Shapiro M, Alter HJ, Purcell RH. Prevention of hepatitis C virus infection in chimpanzees by hyperimmune serum against the hypervariable region 1 of the envelope 2 protein.  Proc. Natl. Acad. Sci. U.S.A.  1996;93;26  Link to Prevention of hepatitis C virus infection in chimpanzees by hyperimmune serum against the hypervariable region 1 of the envelope 2 protein.
  144. Journal Article Yanagi M, Bukh J, Emerson SU, Purcell RH. Contamination of commercially available fetal bovine sera with bovine viral diarrhea virus genomes: implications for the study of hepatitis C virus in cell cultures.  J. Infect. Dis.  1996;174;6  Link to Contamination of commercially available fetal bovine sera with bovine viral diarrhea virus genomes: implications for the study of hepatitis C virus in cell cultures.
  145. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Cohen JI, Moskal T, Shapiro M, Purcell RH. Varicella in Chimpanzees.  J. Med. Virol.  1996;50;4  Link to Varicella in Chimpanzees.
  146. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Funkhouser AW, Raychaudhuri G, Purcell RH, Govindarajan S, Elkins R, Emerson SU. Progress toward the development of a genetically engineered attenuated hepatitis A virus vaccine.  J. Virol.  1996;70;11  Link to Progress toward the development of a genetically engineered attenuated hepatitis A virus vaccine.
  147. Journal Article Yu M, Miller RH, Emerson S, Purcell RH. A hydrophobic heptad repeat of the core protein of woodchuck hepatitis virus is required for capsid assembly.  J. Virol.  1996;70;10  Link to A hydrophobic heptad repeat of the core protein of woodchuck hepatitis virus is required for capsid assembly.
  148. Journal Article Shimizu YK, Igarashi H, Kiyohara T, Cabezon T, Farci P, Purcell RH, Yoshikura H. A hyperimmune serum against a synthetic peptide corresponding to the hypervariable region 1 of hepatitis C virus can prevent viral infection in cell cultures.  Virology  1996;223;2  Link to A hyperimmune serum against a synthetic peptide corresponding to the hypervariable region 1 of hepatitis C virus can prevent viral infection in cell cultures.
  149. Journal Article Heller T, Yin S, Tsarev SA, Purcell RH, Emerson SU. False-positive serologic test resulting from a probable yeast infection in a chimpanzee.  Clin. Diagn. Lab. Immunol.  1996;3;5  Link to False-positive serologic test resulting from a probable yeast infection in a chimpanzee.
  150. Case ReportsJournal Article Farci P, Alter HJ, Shimoda A, Govindarajan S, Cheung LC, Melpolder JC, Sacher RA, Shih JW, Purcell RH. Hepatitis C virus-associated fulminant hepatic failure.  N. Engl. J. Med.  1996;335;9  Link to Hepatitis C virus-associated fulminant hepatic failure.
  151. Comparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S. Davis HL, McCluskie MJ, Gerin JL, Purcell RH. DNA vaccine for hepatitis B: evidence for immunogenicity in chimpanzees and comparison with other vaccines.  Proc. Natl. Acad. Sci. U.S.A.  1996;93;14  Link to DNA vaccine for hepatitis B: evidence for immunogenicity in chimpanzees and comparison with other vaccines.
  152. Journal Article Tellier R, Bukh J, Emerson SU, Purcell RH. Amplification of the full-length hepatitis A virus genome by long reverse transcription-PCR and transcription of infectious RNA directly from the amplicon.  Proc. Natl. Acad. Sci. U.S.A.  1996;93;9  Link to Amplification of the full-length hepatitis A virus genome by long reverse transcription-PCR and transcription of infectious RNA directly from the amplicon.
  153. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Emerson SU, Tsarev SA, Govindarajan S, Shapiro M, Purcell RH. A simian strain of hepatitis A virus, AGM-27, functions as an attenuated vaccine for chimpanzees.  J. Infect. Dis.  1996;173;3  Link to A simian strain of hepatitis A virus, AGM-27, functions as an attenuated vaccine for chimpanzees.
  154. Journal Article Shimizu YK, Feinstone SM, Kohara M, Purcell RH, Yoshikura H. Hepatitis C virus: detection of intracellular virus particles by electron microscopy.  Hepatology  1996;23;2  Link to Hepatitis C virus: detection of intracellular virus particles by electron microscopy.
  155. 1995

  156. Comparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S. Tsarev SA, Tsareva TS, Emerson SU, Rippy MK, Zack P, Shapiro M, Purcell RH. Experimental hepatitis E in pregnant rhesus monkeys: failure to transmit hepatitis E virus (HEV) to offspring and evidence of naturally acquired antibodies to HEV.  J. Infect. Dis.  1995;172;1  Link to Experimental hepatitis E in pregnant rhesus monkeys: failure to transmit hepatitis E virus (HEV) to offspring and evidence of naturally acquired antibodies to HEV.
  157. Journal Article D'Hondt E, Purcell RH, Emerson SU, Wong DC, Shapiro M, Govindarajan S. Efficacy of an inactivated hepatitis A vaccine in pre- and postexposure conditions in marmosets.  J. Infect. Dis.  1995;171 Suppl 1  Link to Efficacy of an inactivated hepatitis A vaccine in pre- and postexposure conditions in marmosets.
  158. Journal ArticleReview Bukh J, Miller RH, Purcell RH. Genetic heterogeneity of hepatitis C virus: quasispecies and genotypes.  Semin. Liver Dis.  1995;15;1  Link to Genetic heterogeneity of hepatitis C virus: quasispecies and genotypes.
  159. Comparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S. Arankalle VA, Tsarev SA, Chadha MS, Alling DW, Emerson SU, Banerjee K, Purcell RH. Age-specific prevalence of antibodies to hepatitis A and E viruses in Pune, India, 1982 and 1992.  J. Infect. Dis.  1995;171;2  Link to Age-specific prevalence of antibodies to hepatitis A and E viruses in Pune, India, 1982 and 1992.
  160. Journal ArticleReview Bukh J, Miller RH, Purcell RH. Genetic heterogeneity of the hepatitis C virus.  Int. Symp. Princess Takamatsu Cancer Res. Fund  1995;25  Link to Genetic heterogeneity of the hepatitis C virus.
  161. Journal ArticleReview Purcell RH. Hepatitis C and its sequelae: the biology of hepatitis C virus and implications for its control.  Int. Symp. Princess Takamatsu Cancer Res. Fund  1995;25  Link to Hepatitis C and its sequelae: the biology of hepatitis C virus and implications for its control.
  162. Clinical TrialJournal ArticleRandomized Controlled Trial Xu ZY, Duan SC, Margolis HS, Purcell RH, Ou-Yang PY, Coleman PJ, Zhuang YL, Xu HF, Qian SG, Zhu QR. Long-term efficacy of active postexposure immunization of infants for prevention of hepatitis B virus infection. United States-People's Republic of China Study Group on Hepatitis B.  J. Infect. Dis.  1995;171;1  Link to Long-term efficacy of active postexposure immunization of infants for prevention of hepatitis B virus infection. United States-People's Republic of China Study Group on Hepatitis B.
  163. 1994

  164. Journal Article Sugata F, Chen HS, Kaneko S, Purcell RH, Miller RH. Analysis of the X gene promoter of woodchuck hepatitis virus.  Virology  1994;205;1  Link to Analysis of the X gene promoter of woodchuck hepatitis virus.
  165. Journal Article Tappero G, Natoli G, Anfossi G, Rosina F, Negro F, Smedile A, Bonino F, Angeli A, Purcell RH, Rizzetto M. Expression of the c-myc protooncogene product in cells infected with the hepatitis delta virus.  Hepatology  1994;20;5  Link to Expression of the c-myc protooncogene product in cells infected with the hepatitis delta virus.
  166. Comparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S. Tsarev SA, Tsareva TS, Emerson SU, Govindarajan S, Shapiro M, Gerin JL, Purcell RH. Successful passive and active immunization of cynomolgus monkeys against hepatitis E.  Proc. Natl. Acad. Sci. U.S.A.  1994;91;21  Link to Successful passive and active immunization of cynomolgus monkeys against hepatitis E.
  167. Comparative StudyJournal Article Bryan JP, Tsarev SA, Iqbal M, Ticehurst J, Emerson S, Ahmed A, Duncan J, Rafiqui AR, Malik IA, Purcell RH. Epidemic hepatitis E in Pakistan: patterns of serologic response and evidence that antibody to hepatitis E virus protects against disease.  J. Infect. Dis.  1994;170;3  Link to Epidemic hepatitis E in Pakistan: patterns of serologic response and evidence that antibody to hepatitis E virus protects against disease.
  168. Comparative StudyJournal Article Yin S, Purcell RH, Emerson SU. A new Chinese isolate of hepatitis E virus: comparison with strains recovered from different geographical regions.  Virus Genes  1994;9;1  Link to A new Chinese isolate of hepatitis E virus: comparison with strains recovered from different geographical regions.
  169. Comparative StudyJournal Article Bukh J, Purcell RH, Miller RH. Sequence analysis of the core gene of 14 hepatitis C virus genotypes.  Proc. Natl. Acad. Sci. U.S.A.  1994;91;17  Link to Sequence analysis of the core gene of 14 hepatitis C virus genotypes.
  170. Comparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S. Farci P, Alter HJ, Wong DC, Miller RH, Govindarajan S, Engle R, Shapiro M, Purcell RH. Prevention of hepatitis C virus infection in chimpanzees after antibody-mediated in vitro neutralization.  Proc. Natl. Acad. Sci. U.S.A.  1994;91;16  Link to Prevention of hepatitis C virus infection in chimpanzees after antibody-mediated in vitro neutralization.
  171. Comparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S. Tsarev SA, Tsareva TS, Emerson SU, Yarbough PO, Legters LJ, Moskal T, Purcell RH. Infectivity titration of a prototype strain of hepatitis E virus in cynomolgus monkeys.  J. Med. Virol.  1994;43;2  Link to Infectivity titration of a prototype strain of hepatitis E virus in cynomolgus monkeys.
  172. Journal Article Arankalle VA, Chadha MS, Tsarev SA, Emerson SU, Risbud AR, Banerjee K, Purcell RH. Seroepidemiology of water-borne hepatitis in India and evidence for a third enterically-transmitted hepatitis agent.  Proc. Natl. Acad. Sci. U.S.A.  1994;91;8  Link to Seroepidemiology of water-borne hepatitis in India and evidence for a third enterically-transmitted hepatitis agent.
  173. Journal ArticleReview Purcell RH. Hepatitis viruses: changing patterns of human disease.  Proc. Natl. Acad. Sci. U.S.A.  1994;91;7  Link to Hepatitis viruses: changing patterns of human disease.
  174. Journal Article Shimizu YK, Hijikata M, Iwamoto A, Alter HJ, Purcell RH, Yoshikura H. Neutralizing antibodies against hepatitis C virus and the emergence of neutralization escape mutant viruses.  J. Virol.  1994;68;3  Link to Neutralizing antibodies against hepatitis C virus and the emergence of neutralization escape mutant viruses.
  175. Journal Article Lai ME, Mazzoleni AP, Argiolu F, De Virgilis S, Balestrieri A, Purcell RH, Cao A, Farci P. Hepatitis C virus in multiple episodes of acute hepatitis in polytransfused thalassaemic children.  Lancet  1994;343;8894  Link to Hepatitis C virus in multiple episodes of acute hepatitis in polytransfused thalassaemic children.
  176. Journal Article Purcell RH, Mannucci PM, Gdovin S, Gringeri A, Colombo M, Mele A, Schinaia N, Ciavarella N, Emerson SU. Virology of the hepatitis A epidemic in Italy.  Vox Sang.  1994;67 Suppl 4  Link to Virology of the hepatitis A epidemic in Italy.
  177. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Mannucci PM, Gdovin S, Gringeri A, Colombo M, Mele A, Schinaia N, Ciavarella N, Emerson SU, Purcell RH. Transmission of hepatitis A to patients with hemophilia by factor VIII concentrates treated with organic solvent and detergent to inactivate viruses. The Italian Collaborative Group.  Ann. Intern. Med.  1994;120;1  Link to Transmission of hepatitis A to patients with hemophilia by factor VIII concentrates treated with organic solvent and detergent to inactivate viruses. The Italian Collaborative Group.
  178. Comparative StudyJournal Article Funkhouser AW, Purcell RH, D'Hondt E, Emerson SU. Attenuated hepatitis A virus: genetic determinants of adaptation to growth in MRC-5 cells.  J. Virol.  1994;68;1  Link to Attenuated hepatitis A virus: genetic determinants of adaptation to growth in MRC-5 cells.
  179. Journal Article Emerson SU, Lewis M, Govindarajan S, Shapiro M, Moskal T, Purcell RH. In vivo transfection by hepatitis A virus synthetic RNA.  Arch. Virol. Suppl.  1994;9  Link to In vivo transfection by hepatitis A virus synthetic RNA.
  180. 1993

  181. Journal Article Bukh J, Wantzin P, Krogsgaard K, Knudsen F, Purcell RH, Miller RH. High prevalence of hepatitis C virus (HCV) RNA in dialysis patients: failure of commercially available antibody tests to identify a significant number of patients with HCV infection. Copenhagen Dialysis HCV Study Group.  J. Infect. Dis.  1993;168;6  Link to High prevalence of hepatitis C virus (HCV) RNA in dialysis patients: failure of commercially available antibody tests to identify a significant number of patients with HCV infection. Copenhagen Dialysis HCV Study Group.
  182. Comparative StudyJournal Article Yin S, Tsarev SA, Purcell RH, Emerson SU. Partial sequence comparison of eight new Chinese strains of hepatitis E virus suggests the genome sequence is relatively stable.  J. Med. Virol.  1993;41;3  Link to Partial sequence comparison of eight new Chinese strains of hepatitis E virus suggests the genome sequence is relatively stable.
  183. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Kew MC, Miller RH, Chen HS, Tennant BC, Purcell RH. Mutant woodchuck hepatitis virus genomes from virions resemble rearranged hepadnaviral integrants in hepatocellular carcinoma.  Proc. Natl. Acad. Sci. U.S.A.  1993;90;21  Link to Mutant woodchuck hepatitis virus genomes from virions resemble rearranged hepadnaviral integrants in hepatocellular carcinoma.
  184. Comparative StudyJournal Article Bukh J, Purcell RH, Miller RH. At least 12 genotypes of hepatitis C virus predicted by sequence analysis of the putative E1 gene of isolates collected worldwide.  Proc. Natl. Acad. Sci. U.S.A.  1993;90;17  Link to At least 12 genotypes of hepatitis C virus predicted by sequence analysis of the putative E1 gene of isolates collected worldwide.
  185. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Tsarev SA, Tsareva TS, Emerson SU, Kapikian AZ, Ticehurst J, London W, Purcell RH. ELISA for antibody to hepatitis E virus (HEV) based on complete open-reading frame-2 protein expressed in insect cells: identification of HEV infection in primates.  J. Infect. Dis.  1993;168;2  Link to ELISA for antibody to hepatitis E virus (HEV) based on complete open-reading frame-2 protein expressed in insect cells: identification of HEV infection in primates.
  186. Comparative StudyJournal Article Shimizu YK, Purcell RH, Yoshikura H. Correlation between the infectivity of hepatitis C virus in vivo and its infectivity in vitro.  Proc. Natl. Acad. Sci. U.S.A.  1993;90;13  Link to Correlation between the infectivity of hepatitis C virus in vivo and its infectivity in vitro.
  187. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Tsarev SA, Emerson SU, Tsareva TS, Yarbough PO, Lewis M, Govindarajan S, Reyes GR, Shapiro M, Purcell RH. Variation in course of hepatitis E in experimentally infected cynomolgus monkeys.  J. Infect. Dis.  1993;167;6  Link to Variation in course of hepatitis E in experimentally infected cynomolgus monkeys.
  188. Journal Article Emerson SU, Huang YK, Purcell RH. 2B and 2C mutations are essential but mutations throughout the genome of HAV contribute to adaptation to cell culture.  Virology  1993;194;2  Link to 2B and 2C mutations are essential but mutations throughout the genome of HAV contribute to adaptation to cell culture.
  189. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Ogata N, Miller RH, Ishak KG, Purcell RH. The complete nucleotide sequence of a pre-core mutant of hepatitis B virus implicated in fulminant hepatitis and its biological characterization in chimpanzees.  Virology  1993;194;1  Link to The complete nucleotide sequence of a pre-core mutant of hepatitis B virus implicated in fulminant hepatitis and its biological characterization in chimpanzees.
  190. Journal Article Ogata N, Ostberg L, Ehrlich PH, Wong DC, Miller RH, Purcell RH. Markedly prolonged incubation period of hepatitis B in a chimpanzee passively immunized with a human monoclonal antibody to the a determinant of hepatitis B surface antigen.  Proc. Natl. Acad. Sci. U.S.A.  1993;90;7  Link to Markedly prolonged incubation period of hepatitis B in a chimpanzee passively immunized with a human monoclonal antibody to the a determinant of hepatitis B surface antigen.
  191. Journal ArticleReview Purcell RH. The discovery of the hepatitis viruses.  Gastroenterology  1993;104;4  Link to The discovery of the hepatitis viruses.
  192. Journal Article Hijikata M, Shimizu YK, Kato H, Iwamoto A, Shih JW, Alter HJ, Purcell RH, Yoshikura H. Equilibrium centrifugation studies of hepatitis C virus: evidence for circulating immune complexes.  J. Virol.  1993;67;4  Link to Equilibrium centrifugation studies of hepatitis C virus: evidence for circulating immune complexes.
  193. Comparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S. Chen HS, Kaneko S, Girones R, Anderson RW, Hornbuckle WE, Tennant BC, Cote PJ, Gerin JL, Purcell RH, Miller RH. The woodchuck hepatitis virus X gene is important for establishment of virus infection in woodchucks.  J. Virol.  1993;67;3  Link to The woodchuck hepatitis virus X gene is important for establishment of virus infection in woodchucks.
  194. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Bukh J, Miller RH, Kew MC, Purcell RH. Hepatitis C virus RNA in southern African blacks with hepatocellular carcinoma.  Proc. Natl. Acad. Sci. U.S.A.  1993;90;5  Link to Hepatitis C virus RNA in southern African blacks with hepatocellular carcinoma.
  195. Comparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S. Kew MC, Chestnut T, Baldwin BH, Hornbuckle WE, Tennant BC, Purcell RH, Miller RH. Heterogeneity of the woodchuck hepatitis virus genome in a chronically infected woodchuck.  Virus Res.  1993;27;3  Link to Heterogeneity of the woodchuck hepatitis virus genome in a chronically infected woodchuck.
  196. Journal ArticleReview Miller RH, Bukh J, Purcell RH. Importance of the polymerase chain reaction in the study of hepatitis C virus infection.  Int. J. Clin. Lab. Res.  1993;23;3  Link to Importance of the polymerase chain reaction in the study of hepatitis C virus infection.
  197. Journal Article Tedeschi V, Purcell RH, Emerson SU. Partial characterization of hepatitis A viruses from three intermediate passage levels of a series resulting in adaptation to growth in cell culture and attenuation of virulence.  J. Med. Virol.  1993;39;1  Link to Partial characterization of hepatitis A viruses from three intermediate passage levels of a series resulting in adaptation to growth in cell culture and attenuation of virulence.
  198. Journal ArticleReview Purcell RH. Control of hepatitis A by inactivated vaccines: unanswered questions and unresolved issues.  J. Hepatol.  1993;18 Suppl 2  Link to Control of hepatitis A by inactivated vaccines: unanswered questions and unresolved issues.
  199. 1992

  200. Journal Article Emerson SU, Lewis M, Govindarajan S, Shapiro M, Moskal T, Purcell RH. cDNA clone of hepatitis A virus encoding a virulent virus: induction of viral hepatitis by direct nucleic acid transfection of marmosets.  J. Virol.  1992;66;11  Link to cDNA clone of hepatitis A virus encoding a virulent virus: induction of viral hepatitis by direct nucleic acid transfection of marmosets.
  201. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Chen HS, Kew MC, Hornbuckle WE, Tennant BC, Cote PJ, Gerin JL, Purcell RH, Miller RH. The precore gene of the woodchuck hepatitis virus genome is not essential for viral replication in the natural host.  J. Virol.  1992;66;9  Link to The precore gene of the woodchuck hepatitis virus genome is not essential for viral replication in the natural host.
  202. Journal Article Shimizu YK, Iwamoto A, Hijikata M, Purcell RH, Yoshikura H. Evidence for in vitro replication of hepatitis C virus genome in a human T-cell line.  Proc. Natl. Acad. Sci. U.S.A.  1992;89;12  Link to Evidence for in vitro replication of hepatitis C virus genome in a human T-cell line.
  203. Comparative StudyJournal Article Bukh J, Purcell RH, Miller RH. Sequence analysis of the 5' noncoding region of hepatitis C virus.  Proc. Natl. Acad. Sci. U.S.A.  1992;89;11  Link to Sequence analysis of the 5' noncoding region of hepatitis C virus.
  204. Comparative StudyJournal Article Farci P, London WT, Wong DC, Dawson GJ, Vallari DS, Engle R, Purcell RH. The natural history of infection with hepatitis C virus (HCV) in chimpanzees: comparison of serologic responses measured with first- and second-generation assays and relationship to HCV viremia.  J. Infect. Dis.  1992;165;6  Link to The natural history of infection with hepatitis C virus (HCV) in chimpanzees: comparison of serologic responses measured with first- and second-generation assays and relationship to HCV viremia.
  205. Journal Article Kelen GD, Green GB, Purcell RH, Chan DW, Qaqish BF, Sivertson KT, Quinn TC. Hepatitis B and hepatitis C in emergency department patients.  N. Engl. J. Med.  1992;326;21  Link to Hepatitis B and hepatitis C in emergency department patients.
  206. Journal Article Negro F, Pacchioni D, Shimizu Y, Miller RH, Bussolati G, Purcell RH, Bonino F. Detection of intrahepatic replication of hepatitis C virus RNA by in situ hybridization and comparison with histopathology.  Proc. Natl. Acad. Sci. U.S.A.  1992;89;6  Link to Detection of intrahepatic replication of hepatitis C virus RNA by in situ hybridization and comparison with histopathology.
  207. Journal Article Emerson SU, Huang YK, McRill C, Lewis M, Purcell RH. Mutations in both the 2B and 2C genes of hepatitis A virus are involved in adaptation to growth in cell culture.  J. Virol.  1992;66;2  Link to Mutations in both the 2B and 2C genes of hepatitis A virus are involved in adaptation to growth in cell culture.
  208. Comparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S. Tsarev SA, Emerson SU, Reyes GR, Tsareva TS, Legters LJ, Malik IA, Iqbal M, Purcell RH. Characterization of a prototype strain of hepatitis E virus.  Proc. Natl. Acad. Sci. U.S.A.  1992;89;2  Link to Characterization of a prototype strain of hepatitis E virus.
  209. Journal Article Bukh J, Purcell RH, Miller RH. Importance of primer selection for the detection of hepatitis C virus RNA with the polymerase chain reaction assay.  Proc. Natl. Acad. Sci. U.S.A.  1992;89;1  Link to Importance of primer selection for the detection of hepatitis C virus RNA with the polymerase chain reaction assay.
  210. Journal Article Emerson SU, Huang YK, McRill C, Lewis M, Shapiro M, London WT, Purcell RH. Molecular basis of virulence and growth of hepatitis A virus in cell culture.  Vaccine  1992;10 Suppl 1  Link to Molecular basis of virulence and growth of hepatitis A virus in cell culture.
  211. Comparative StudyJournal Article Purcell RH, D'Hondt E, Bradbury R, Emerson SU, Govindarajan S, Binn L. Inactivated hepatitis A vaccine: active and passive immunoprophylaxis in chimpanzees.  Vaccine  1992;10 Suppl 1  Link to Inactivated hepatitis A vaccine: active and passive immunoprophylaxis in chimpanzees.
  212. Clinical TrialControlled Clinical TrialJournal Article Sjogren MH, Purcell RH, McKee K, Binn L, Macarthy P, Ticehurst J, Feinstone S, Caudill J, See A, Hoke C. Clinical and laboratory observations following oral or intramuscular administration of a live attenuated hepatitis A vaccine candidate.  Vaccine  1992;10 Suppl 1  Link to Clinical and laboratory observations following oral or intramuscular administration of a live attenuated hepatitis A vaccine candidate.
  213. 1991

  214. Journal Article Kiyosawa K, Sodeyama T, Tanaka E, Nakano Y, Furuta S, Nishioka K, Purcell RH, Alter HJ. Hepatitis C in hospital employees with needlestick injuries.  Ann. Intern. Med.  1991;115;5  Link to Hepatitis C in hospital employees with needlestick injuries.
  215. In VitroJournal Article Emerson SU, McRill C, Rosenblum B, Feinstone S, Purcell RH. Mutations responsible for adaptation of hepatitis A virus to efficient growth in cell culture.  J. Virol.  1991;65;9  Link to Mutations responsible for adaptation of hepatitis A virus to efficient growth in cell culture.
  216. Journal Article Farci P, Alter HJ, Wong D, Miller RH, Shih JW, Jett B, Purcell RH. A long-term study of hepatitis C virus replication in non-A, non-B hepatitis.  N. Engl. J. Med.  1991;325;2  Link to A long-term study of hepatitis C virus replication in non-A, non-B hepatitis.
  217. Comparative StudyJournal Article Tsarev SA, Emerson SU, Balayan MS, Ticehurst J, Purcell RH. Simian hepatitis A virus (HAV) strain AGM-27: comparison of genome structure and growth in cell culture with other HAV strains.  J. Gen. Virol.  1991;72 ( Pt 7)  Link to Simian hepatitis A virus (HAV) strain AGM-27: comparison of genome structure and growth in cell culture with other HAV strains.
  218. Journal Article Ogata N, Alter HJ, Miller RH, Purcell RH. Nucleotide sequence and mutation rate of the H strain of hepatitis C virus.  Proc. Natl. Acad. Sci. U.S.A.  1991;88;8  Link to Nucleotide sequence and mutation rate of the H strain of hepatitis C virus.
  219. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Jupp PG, Purcell RH, Phillips JM, Shapiro M, Gerin JL. Attempts to transmit hepatitis B virus to chimpanzees by arthropods.  S. Afr. Med. J.  1991;79;6  Link to Attempts to transmit hepatitis B virus to chimpanzees by arthropods.
  220. Journal ArticleReview Purcell RH, Miller RH. The nature of genetic variation among viruses.  J. Hepatol.  1991;13 Suppl 4  Link to The nature of genetic variation among viruses.
  221. Comparative StudyJournal ArticleReview Emerson SU, Tsarev SA, Purcell RH. Biological and molecular comparisons of human (HM-175) and simian (AGM-27) hepatitis A viruses.  J. Hepatol.  1991;13 Suppl 4  Link to Biological and molecular comparisons of human (HM-175) and simian (AGM-27) hepatitis A viruses.
  222. 1990

  223. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Miller RH, Girones R, Cote PJ, Hornbuckle WE, Chestnut T, Baldwin BH, Korba BE, Tennant BC, Gerin JL, Purcell RH. Evidence against a requisite role for defective virus in the establishment of persistent hepadnavirus infections.  Proc. Natl. Acad. Sci. U.S.A.  1990;87;23  Link to Evidence against a requisite role for defective virus in the establishment of persistent hepadnavirus infections.
  224. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Tassopoulos NC, Sjogren MH, Purcell RH. 19S and 7-8S forms of IgM antibody to hepatitis B core antigen in acute icteric hepatitis superimposed on hepatitis B surface antigen carriage.  Infection  1990;18;6  Link to 19S and 7-8S forms of IgM antibody to hepatitis B core antigen in acute icteric hepatitis superimposed on hepatitis B surface antigen carriage.
  225. Journal Article Kiyosawa K, Sodeyama T, Tanaka E, Gibo Y, Yoshizawa K, Nakano Y, Furuta S, Akahane Y, Nishioka K, Purcell RH. Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: analysis by detection of antibody to hepatitis C virus.  Hepatology  1990;12;4 Pt 1  Link to Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: analysis by detection of antibody to hepatitis C virus.
  226. Comparative StudyLetter Wong DC, Diwan AR, Rosen L, Gerin JL, Johnson RG, Polito A, Purcell RH. Non-specificity of anti-HCV test for seroepidemiological analysis.  Lancet  1990;336;8717  Link to Non-specificity of anti-HCV test for seroepidemiological analysis.
  227. Comparative StudyJournal Article Kaneko S, Miller RH, Di Bisceglie A, Feinstone SM, Hoofnagle JH, Purcell RH. Hepatitis B virus DNA detection and comparison with hepatitis B surface antigen.  Gastroenterol. Jpn.  1990;25 Suppl 2  Link to Hepatitis B virus DNA detection and comparison with hepatitis B surface antigen.
  228. Journal Article Kaneko S, Miller RH, Di Bisceglie AM, Feinstone SM, Hoofnagle JH, Purcell RH. Detection of hepatitis B virus DNA in serum by polymerase chain reaction. Application for clinical diagnosis.  Gastroenterology  1990;99;3  Link to Detection of hepatitis B virus DNA in serum by polymerase chain reaction. Application for clinical diagnosis.
  229. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Shimizu YK, Weiner AJ, Rosenblatt J, Wong DC, Shapiro M, Popkin T, Houghton M, Alter HJ, Purcell RH. Early events in hepatitis C virus infection of chimpanzees.  Proc. Natl. Acad. Sci. U.S.A.  1990;87;16  Link to Early events in hepatitis C virus infection of chimpanzees.
  230. Journal Article Collins PL, Purcell RH, London WT, Lawrence LA, Chanock RM, Murphy BR. Evaluation in chimpanzees of vaccinia virus recombinants that express the surface glycoproteins of human respiratory syncytial virus.  Vaccine  1990;8;2  Link to Evaluation in chimpanzees of vaccinia virus recombinants that express the surface glycoproteins of human respiratory syncytial virus.
  231. Comparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S. Miller RH, Purcell RH. Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroups.  Proc. Natl. Acad. Sci. U.S.A.  1990;87;6  Link to Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroups.
  232. Journal Article Dienes HP, Purcell RH, Popper H, Ponzetto A. The significance of infections with two types of viral hepatitis demonstrated by histologic features in chimpanzees.  J. Hepatol.  1990;10;1  Link to The significance of infections with two types of viral hepatitis demonstrated by histologic features in chimpanzees.
  233. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Smedile A, Bergmann KF, Baroudy BM, Wells FV, Purcell RH, Bonino F, Rizzetto M, Gerin JL. Riboprobe assay for HDV RNA: a sensitive method for the detection of the HDV genome in clinical serum samples.  J. Med. Virol.  1990;30;1  Link to Riboprobe assay for HDV RNA: a sensitive method for the detection of the HDV genome in clinical serum samples.
  234. Journal ArticleReview Purcell RH. Enterically transmitted non-A, non-B hepatitis.  Prog Liver Dis  1990;9  Link to Enterically transmitted non-A, non-B hepatitis.
  235. 1989

  236. Journal Article Cohen JI, Rosenblum B, Feinstone SM, Ticehurst J, Purcell RH. Attenuation and cell culture adaptation of hepatitis A virus (HAV): a genetic analysis with HAV cDNA.  J. Virol.  1989;63;12  Link to Attenuation and cell culture adaptation of hepatitis A virus (HAV): a genetic analysis with HAV cDNA.
  237. Journal Article Alter HJ, Purcell RH, Shih JW, Melpolder JC, Houghton M, Choo QL, Kuo G. Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis.  N. Engl. J. Med.  1989;321;22  Link to Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis.
  238. Journal Article Cohen JI, Feinstone S, Purcell RH. Hepatitis A virus infection in a chimpanzee: duration of viremia and detection of virus in saliva and throat swabs.  J. Infect. Dis.  1989;160;5  Link to Hepatitis A virus infection in a chimpanzee: duration of viremia and detection of virus in saliva and throat swabs.
  239. Journal Article Shimizu YK, Purcell RH. Cytoplasmic antigen in hepatocytes of chimpanzees infected with non-A, non-B hepatitis virus or hepatitis delta virus: relationship to interferon.  Hepatology  1989;10;5  Link to Cytoplasmic antigen in hepatocytes of chimpanzees infected with non-A, non-B hepatitis virus or hepatitis delta virus: relationship to interferon.
  240. Comparative StudyJournal Article Olmsted RA, Hirsch VM, Purcell RH, Johnson PR. Nucleotide sequence analysis of feline immunodeficiency virus: genome organization and relationship to other lentiviruses.  Proc. Natl. Acad. Sci. U.S.A.  1989;86;20  Link to Nucleotide sequence analysis of feline immunodeficiency virus: genome organization and relationship to other lentiviruses.
  241. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Korba BE, Cote PJ, Shapiro M, Purcell RH, Gerin JL. In vitro production of infectious woodchuck hepatitis virus by lipopolysaccharide-stimulated peripheral blood lymphocytes.  J. Infect. Dis.  1989;160;4  Link to In vitro production of infectious woodchuck hepatitis virus by lipopolysaccharide-stimulated peripheral blood lymphocytes.
  242. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Negro F, Shapiro M, Satterfield WC, Gerin JL, Purcell RH. Reappearance of hepatitis D virus (HDV) replication in chronic hepatitis B virus carrier chimpanzees rechallenged with HDV.  J. Infect. Dis.  1989;160;4  Link to Reappearance of hepatitis D virus (HDV) replication in chronic hepatitis B virus carrier chimpanzees rechallenged with HDV.
  243. CommentLetter Negro F, Gerin JL, Purcell RH, Miller RH. Basis of hepatitis delta virus disease?  Nature  1989;341;6238  Link to Basis of hepatitis delta virus disease?
  244. Comparative StudyJournal Article Hirsch VM, Olmsted RA, Murphey-Corb M, Purcell RH, Johnson PR. An African primate lentivirus (SIVsm) closely related to HIV-2.  Nature  1989;339;6223  Link to An African primate lentivirus (SIVsm) closely related to HIV-2.
  245. Journal Article Kuo G, Choo QL, Alter HJ, Gitnick GL, Redeker AG, Purcell RH, Miyamura T, Dienstag JL, Alter MJ, Stevens CE. An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis.  Science  1989;244;4902  Link to An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis.
  246. Journal Article Olmsted RA, Barnes AK, Yamamoto JK, Hirsch VM, Purcell RH, Johnson PR. Molecular cloning of feline immunodeficiency virus.  Proc. Natl. Acad. Sci. U.S.A.  1989;86;7  Link to Molecular cloning of feline immunodeficiency virus.
  247. Journal Article Koenig S, Hirsch VM, Olmsted RA, Powell D, Maury W, Rabson A, Fauci AS, Purcell RH, Johnson PR. Selective infection of human CD4+ cells by simian immunodeficiency virus: productive infection associated with envelope glycoprotein-induced fusion.  Proc. Natl. Acad. Sci. U.S.A.  1989;86;7  Link to Selective infection of human CD4+ cells by simian immunodeficiency virus: productive infection associated with envelope glycoprotein-induced fusion.
  248. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Girones R, Cote PJ, Hornbuckle WE, Tennant BC, Gerin JL, Purcell RH, Miller RH. Complete nucleotide sequence of a molecular clone of woodchuck hepatitis virus that is infectious in the natural host.  Proc. Natl. Acad. Sci. U.S.A.  1989;86;6  Link to Complete nucleotide sequence of a molecular clone of woodchuck hepatitis virus that is infectious in the natural host.
  249. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Korba BE, Cote PJ, Wells FV, Baldwin B, Popper H, Purcell RH, Tennant BC, Gerin JL. Natural history of woodchuck hepatitis virus infections during the course of experimental viral infection: molecular virologic features of the liver and lymphoid tissues.  J. Virol.  1989;63;3  Link to Natural history of woodchuck hepatitis virus infections during the course of experimental viral infection: molecular virologic features of the liver and lymphoid tissues.
  250. Journal ArticleReview Fauci AS, Gallo RC, Koenig S, Salk J, Purcell RH. NIH conference. Development and evaluation of a vaccine for human immunodeficiency virus (HIV) infection.  Ann. Intern. Med.  1989;110;5  Link to NIH conference. Development and evaluation of a vaccine for human immunodeficiency virus (HIV) infection.
  251. Journal ArticleReview Miller RH, Kaneko S, Chung CT, Girones R, Purcell RH. Compact organization of the hepatitis B virus genome.  Hepatology  1989;9;2  Link to Compact organization of the hepatitis B virus genome.
  252. Comparative StudyJournal Article Kaneko S, Miller RH, Feinstone SM, Unoura M, Kobayashi K, Hattori N, Purcell RH. Detection of serum hepatitis B virus DNA in patients with chronic hepatitis using the polymerase chain reaction assay.  Proc. Natl. Acad. Sci. U.S.A.  1989;86;1  Link to Detection of serum hepatitis B virus DNA in patients with chronic hepatitis using the polymerase chain reaction assay.
  253. Journal Article He LF, Ford E, Purcell RH, London WT, Phillips J, Gerin JL. The size of the hepatitis delta agent.  J. Med. Virol.  1989;27;1  Link to The size of the hepatitis delta agent.
  254. Journal Article Purcell RH. Does non-A, non-B hepatitis cause hepatocellular carcinoma?  Cancer Detect. Prev.  1989;14;2  Link to Does non-A, non-B hepatitis cause hepatocellular carcinoma?
  255. Journal Article Tassopoulos NC, Theodoropoulos G, Sjogren MH, Engle R, Purcell RH. Serological markers of hepatitis B virus and hepatitis D virus infections in Greek adults with primary hepatocellular carcinoma.  Infection  1989;17;1  Link to Serological markers of hepatitis B virus and hepatitis D virus infections in Greek adults with primary hepatocellular carcinoma.
  256. 1988

  257. Congresses Purcell RH, Blum HE. Molecular analysis of hepatitis B virus infection.  Transfus Med Rev  1988;2;4  Link to Molecular analysis of hepatitis B virus infection.
  258. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Ponzetto A, Negro F, Popper H, Bonino F, Engle R, Rizzetto M, Purcell RH, Gerin JL. Serial passage of hepatitis delta virus in chronic hepatitis B virus carrier chimpanzees.  Hepatology  1988;8;6  Link to Serial passage of hepatitis delta virus in chronic hepatitis B virus carrier chimpanzees.
  259. Journal Article Gowans EJ, Baroudy BM, Negro F, Ponzetto A, Purcell RH, Gerin JL. Evidence for replication of hepatitis delta virus RNA in hepatocyte nuclei after in vivo infection.  Virology  1988;167;1  Link to Evidence for replication of hepatitis delta virus RNA in hepatocyte nuclei after in vivo infection.
  260. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Negro F, Bergmann KF, Baroudy BM, Satterfield WC, Popper H, Purcell RH, Gerin JL. Chronic hepatitis D virus (HDV) infection in hepatitis B virus carrier chimpanzees experimentally superinfected with HDV.  J. Infect. Dis.  1988;158;1  Link to Chronic hepatitis D virus (HDV) infection in hepatitis B virus carrier chimpanzees experimentally superinfected with HDV.
  261. Journal Article Johnson PR, Parks DE, Norrby E, Lerner RA, Purcell RH, Chanock RM. Site-directed ELISA identifies a highly antigenic region of the simian immunodeficiency virus transmembrane glycoprotein.  AIDS Res. Hum. Retroviruses  1988;4;3  Link to Site-directed ELISA identifies a highly antigenic region of the simian immunodeficiency virus transmembrane glycoprotein.
  262. Journal Article Ramalingaswami V, Purcell RH. Waterborne non-A, non-B hepatitis.  Lancet  1988;1;8585  Link to Waterborne non-A, non-B hepatitis.
  263. Comparative StudyJournal Article Arankalle VA, Ticehurst J, Sreenivasan MA, Kapikian AZ, Popper H, Pavri KM, Purcell RH. Aetiological association of a virus-like particle with enterically transmitted non-A, non-B hepatitis.  Lancet  1988;1;8585  Link to Aetiological association of a virus-like particle with enterically transmitted non-A, non-B hepatitis.
  264. Journal Article Karron RA, Daemer R, Ticehurst J, D'Hondt E, Popper H, Mihalik K, Phillips J, Feinstone S, Purcell RH. Studies of prototype live hepatitis A virus vaccines in primate models.  J. Infect. Dis.  1988;157;2  Link to Studies of prototype live hepatitis A virus vaccines in primate models.
  265. Comparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S. Cohen JI, Miller RH, Rosenblum B, Denniston K, Gerin JL, Purcell RH. Sequence comparison of woodchuck hepatitis virus replicative forms shows conservation of the genome.  Virology  1988;162;1  Link to Sequence comparison of woodchuck hepatitis virus replicative forms shows conservation of the genome.
  266. 1987

  267. Journal Article Tassopoulos NC, Papaevangelou GJ, Roumeliotou-Karayannis A, Ticehurst JR, Feinstone SM, Purcell RH. Detection of hepatitis B virus DNA in asymptomatic hepatitis B surface antigen carriers: relation to sexual transmission.  Am. J. Epidemiol.  1987;126;4  Link to Detection of hepatitis B virus DNA in asymptomatic hepatitis B surface antigen carriers: relation to sexual transmission.
  268. Journal Article He LF, Alling D, Popkin T, Shapiro M, Alter HJ, Purcell RH. Determining the size of non-A, non-B hepatitis virus by filtration.  J. Infect. Dis.  1987;156;4  Link to Determining the size of non-A, non-B hepatitis virus by filtration.
  269. Journal ArticleReview Gust ID, Purcell RH. Report of a workshop: waterborne non-A, non-B hepatitis.  J. Infect. Dis.  1987;156;4  Link to Report of a workshop: waterborne non-A, non-B hepatitis.
  270. Journal Article Cohen JI, Ticehurst JR, Feinstone SM, Rosenblum B, Purcell RH. Hepatitis A virus cDNA and its RNA transcripts are infectious in cell culture.  J. Virol.  1987;61;10  Link to Hepatitis A virus cDNA and its RNA transcripts are infectious in cell culture.
  271. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Pohl C, Baroudy BM, Bergmann KF, Cote PJ, Purcell RH, Hoofnagle J, Gerin JL. A human monoclonal antibody that recognizes viral polypeptides and in vitro translation products of the genome of the hepatitis D virus.  J. Infect. Dis.  1987;156;4  Link to A human monoclonal antibody that recognizes viral polypeptides and in vitro translation products of the genome of the hepatitis D virus.
  272. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Acs G, Sells MA, Purcell RH, Price P, Engle R, Shapiro M, Popper H. Hepatitis B virus produced by transfected Hep G2 cells causes hepatitis in chimpanzees.  Proc. Natl. Acad. Sci. U.S.A.  1987;84;13  Link to Hepatitis B virus produced by transfected Hep G2 cells causes hepatitis in chimpanzees.
  273. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Tassopoulos NC, Papaevangelou GJ, Sjogren MH, Roumeliotou-Karayannis A, Gerin JL, Purcell RH. Natural history of acute hepatitis B surface antigen-positive hepatitis in Greek adults.  Gastroenterology  1987;92;6  Link to Natural history of acute hepatitis B surface antigen-positive hepatitis in Greek adults.
  274. Journal Article Cohen JI, Rosenblum B, Ticehurst JR, Daemer RJ, Feinstone SM, Purcell RH. Complete nucleotide sequence of an attenuated hepatitis A virus: comparison with wild-type virus.  Proc. Natl. Acad. Sci. U.S.A.  1987;84;8  Link to Complete nucleotide sequence of an attenuated hepatitis A virus: comparison with wild-type virus.
  275. Journal Article Aragona M, Macagno S, Caredda F, Crivelli O, Lavarini C, Maran E, Farci P, Purcell RH, Rizzetto M. Serological response to the hepatitis delta virus in hepatitis D.  Lancet  1987;1;8531  Link to Serological response to the hepatitis delta virus in hepatitis D.
  276. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Popper H, Roth L, Purcell RH, Tennant BC, Gerin JL. Hepatocarcinogenicity of the woodchuck hepatitis virus.  Proc. Natl. Acad. Sci. U.S.A.  1987;84;3  Link to Hepatocarcinogenicity of the woodchuck hepatitis virus.
  277. Journal Article Tassopoulos NC, Roumeliotou-Karayannis A, Sakka M, Ticehurst J, Mihalik K, Stephanou T, Purcell RH, Papaevangelou G. An epidemic of hepatitis A in an institution for young children.  Am. J. Epidemiol.  1987;125;2  Link to An epidemic of hepatitis A in an institution for young children.
  278. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Ponzetto A, Hoyer BH, Popper H, Engle R, Purcell RH, Gerin JL. Titration of the infectivity of hepatitis D virus in chimpanzees.  J. Infect. Dis.  1987;155;1  Link to Titration of the infectivity of hepatitis D virus in chimpanzees.
  279. Comparative StudyJournal Article Cohen JI, Ticehurst JR, Purcell RH, Buckler-White A, Baroudy BM. Complete nucleotide sequence of wild-type hepatitis A virus: comparison with different strains of hepatitis A virus and other picornaviruses.  J. Virol.  1987;61;1  Link to Complete nucleotide sequence of wild-type hepatitis A virus: comparison with different strains of hepatitis A virus and other picornaviruses.
  280. 1986

  281. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Cote PJ, Shapiro M, Engle RE, Popper H, Purcell RH, Gerin JL. Protection of chimpanzees from type B hepatitis by immunization with woodchuck hepatitis virus surface antigen.  J. Virol.  1986;60;3  Link to Protection of chimpanzees from type B hepatitis by immunization with woodchuck hepatitis virus surface antigen.
  282. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Pohl CJ, Cote PJ, Purcell RH, Gerin JL. Failure to detect polyalbumin-binding sites on the woodchuck hepatitis virus surface antigen: implications for the pathogenesis of hepatitis B virus in humans.  J. Virol.  1986;60;3  Link to Failure to detect polyalbumin-binding sites on the woodchuck hepatitis virus surface antigen: implications for the pathogenesis of hepatitis B virus in humans.
  283. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Tassopoulos NC, Papaevangelou GJ, Roumeliotou-Karayannis A, Smedile A, Engle R, Ticehurst JR, Feinstone SM, Purcell RH. Fulminant hepatitis in asymptomatic hepatitis B surface antigen carriers in Greece.  J. Med. Virol.  1986;20;4  Link to Fulminant hepatitis in asymptomatic hepatitis B surface antigen carriers in Greece.
  284. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Smedile A, Rizzetto M, Denniston K, Bonino F, Wells F, Verme G, Consolo F, Hoyer B, Purcell RH, Gerin JL. Type D hepatitis: the clinical significance of hepatitis D virus RNA in serum as detected by a hybridization-based assay.  Hepatology  1986;6;6  Link to Type D hepatitis: the clinical significance of hepatitis D virus RNA in serum as detected by a hybridization-based assay.
  285. Journal Article Buitrago B, Hadler SC, Popper H, Thung SN, Gerber MA, Purcell RH, Maynard JE. Epidemiologic aspects of Santa Marta hepatitis over a 40-year period.  Hepatology  1986;6;6  Link to Epidemiologic aspects of Santa Marta hepatitis over a 40-year period.
  286. Journal Article Buitrago B, Popper H, Hadler SC, Thung SN, Gerber MA, Purcell RH, Maynard JE. Specific histologic features of Santa Marta hepatitis: a severe form of hepatitis delta-virus infection in northern South America.  Hepatology  1986;6;6  Link to Specific histologic features of Santa Marta hepatitis: a severe form of hepatitis delta-virus infection in northern South America.
  287. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Shimizu YK, Purcell RH, Gerin JL, Feinstone SM, Ono Y, Shikata T. Further studies by immunofluorescence of the monoclonal antibodies associated with experimental non-A, non-B hepatitis in chimpanzees and their relation to D hepatitis.  Hepatology  1986;6;6  Link to Further studies by immunofluorescence of the monoclonal antibodies associated with experimental non-A, non-B hepatitis in chimpanzees and their relation to D hepatitis.
  288. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Tassopoulos NC, Sjogren MH, Ticehurst JR, Engle RE, Roumeliotou-Karayannis A, Gerin JL, Purcell RH, Papaevangelou G. Significance of IgM antibody to hepatitis B core antigen in a Greek population with chronic hepatitis B virus infection.  Liver  1986;6;5  Link to Significance of IgM antibody to hepatitis B core antigen in a Greek population with chronic hepatitis B virus infection.
  289. Comparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S. Weitz M, Baroudy BM, Maloy WL, Ticehurst JR, Purcell RH. Detection of a genome-linked protein (VPg) of hepatitis A virus and its comparison with other picornaviral VPgs.  J. Virol.  1986;60;1  Link to Detection of a genome-linked protein (VPg) of hepatitis A virus and its comparison with other picornaviral VPgs.
  290. Journal Article Quinnan GV, Wells MA, Wittek AE, Phelan MA, Mayner RE, Feinstone S, Purcell RH, Epstein JS. Inactivation of human T-cell lymphotropic virus, type III by heat, chemicals, and irradiation.  Transfusion  1986;26;5  Link to Inactivation of human T-cell lymphotropic virus, type III by heat, chemicals, and irradiation.
  291. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Tassopoulos NC, Papaevangelou GJ, Roumeliotou-Karayiannis A, Sjogren MH, Engle R, Karpodini E, Purcell RH. Serologic markers of hepatitis B virus (HBV) and hepatitis D virus infection in carriers of hepatitis B surface antigen who are frequently exposed to HBV.  Hepatogastroenterology  1986;33;4  Link to Serologic markers of hepatitis B virus (HBV) and hepatitis D virus infection in carriers of hepatitis B surface antigen who are frequently exposed to HBV.
  292. Journal Article Tassopoulos NC, Papaevangelou GJ, Ticehurst JR, Purcell RH. Fecal excretion of Greek strains of hepatitis A virus in patients with hepatitis A and in experimentally infected chimpanzees.  J. Infect. Dis.  1986;154;2  Link to Fecal excretion of Greek strains of hepatitis A virus in patients with hepatitis A and in experimentally infected chimpanzees.
  293. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Korba BE, Wells F, Tennant BC, Yoakum GH, Purcell RH, Gerin JL. Hepadnavirus infection of peripheral blood lymphocytes in vivo: woodchuck and chimpanzee models of viral hepatitis.  J. Virol.  1986;58;1  Link to Hepadnavirus infection of peripheral blood lymphocytes in vivo: woodchuck and chimpanzee models of viral hepatitis.
  294. Journal Article Koziol DE, Holland PV, Alling DW, Melpolder JC, Solomon RE, Purcell RH, Hudson LM, Shoup FJ, Krakauer H, Alter HJ. Antibody to hepatitis B core antigen as a paradoxical marker for non-A, non-B hepatitis agents in donated blood.  Ann. Intern. Med.  1986;104;4  Link to Antibody to hepatitis B core antigen as a paradoxical marker for non-A, non-B hepatitis agents in donated blood.
  295. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Paul DA, Purcell RH, Peterson DL. Use of monoclonal antibodies to determine if HBsAg of mixed subtype is one particle or two.  J. Virol. Methods  1986;13;1  Link to Use of monoclonal antibodies to determine if HBsAg of mixed subtype is one particle or two.
  296. Journal ArticleReview Rizzetto M, Ponzetto A, Bonino F, Purcell RH. Superimposed hepatitis and the effect on viral replication in chronic hepatitis B.  J. Hepatol.  1986;3 Suppl 2  Link to Superimposed hepatitis and the effect on viral replication in chronic hepatitis B.
  297. Journal ArticleReview Rizzetto M, Verme G, Gerin JL, Purcell RH. Hepatitis delta virus disease.  Prog Liver Dis  1986;8  Link to Hepatitis delta virus disease.
  298. Journal Article Tassopoulos NC, Papaevangelou GJ, Roumeliotou-Karayannis A, Ticehurst JR, Feinstone SM, Purcell RH. Search for hepatitis B virus DNA in sera from patients with acute type B or non-A, non-B hepatitis.  J. Hepatol.  1986;2;3  Link to Search for hepatitis B virus DNA in sera from patients with acute type B or non-A, non-B hepatitis.
  299. 1985

  300. Letter Tassopoulos NC, Papaevangelou G, Sjogrent MH, Roumeliotou A, Purcell RH. IgM antibody to hepatitis B core antigen: a marker of infectivity.  N. Engl. J. Med.  1985;313;26  Link to IgM antibody to hepatitis B core antigen: a marker of infectivity.
  301. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Tassopoulos N, Papaevangelou G, Roumeliotou-Karayannis A, Kalafatas P, Engle R, Gerin J, Purcell RH. Double infections with hepatitis A and B viruses.  Liver  1985;5;6  Link to Double infections with hepatitis A and B viruses.
  302. Journal Article Shiels MT, Czaja AJ, Taswell HF, Gerin JL, Purcell RH, Ludwig J, Rakela J, Nelson CA. Frequency and significance of delta antibody in acute and chronic hepatitis B. A United States experience.  Gastroenterology  1985;89;6  Link to Frequency and significance of delta antibody in acute and chronic hepatitis B. A United States experience.
  303. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Purcell RH, Gerin JL, Popper H, London WT, Cicmanec J, Eichberg JW, Newman J, Hrinda ME. Hepatitis B virus, hepatitis non-A, non-B virus and hepatitis delta virus in lyophilized antihemophilic factor: relative sensitivity to heat.  Hepatology  1985;5;6  Link to Hepatitis B virus, hepatitis non-A, non-B virus and hepatitis delta virus in lyophilized antihemophilic factor: relative sensitivity to heat.
  304. Letter Tassopoulos NC, Papaevangelou GJ, Roumeliotoi-Karayannis K, Purcell RH. Reactivation of chronic hepatitis B as acute viral hepatitis.  Ann. Intern. Med.  1985;103;3  Link to Reactivation of chronic hepatitis B as acute viral hepatitis.
  305. Clinical TrialJournal ArticleRandomized Controlled Trial Xu ZY, Francis DP, Liu CB, Purcell RH, Duan SC, Chen RJ, Wen YM. Prevention of hepatitis B virus carriage of infants using HBV vaccine in Shanghai. Preliminary report of a randomized double-blind placebo-controlled trial.  Chin. Med. J.  1985;98;9  Link to Prevention of hepatitis B virus carriage of infants using HBV vaccine in Shanghai. Preliminary report of a randomized double-blind placebo-controlled trial.
  306. Journal Article Kiyosawa K, Daemer RJ, He LF, Bonino F, Prozesky OW, Purcell RH. The spectrum of complement-fixing antinuclear antibodies in patients with hepatocellular carcinoma.  Hepatology  1985;5;4  Link to The spectrum of complement-fixing antinuclear antibodies in patients with hepatocellular carcinoma.
  307. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Ponzetto A, Cote PJ, Ford EC, Engle R, Cicmanec J, Shapiro M, Purcell RH, Gerin JL. Radioimmunoassay and characterization of woodchuck hepatitis virus core antigen and antibody.  Virus Res.  1985;2;4  Link to Radioimmunoassay and characterization of woodchuck hepatitis virus core antigen and antibody.
  308. Letter Shiraishi H, Wong D, Purcell RH, Shirachi R, Kumasaka E, Numazaki Y. Antibody to human parvovirus in outbreak of erythema infectiosum in Japan.  Lancet  1985;1;8435  Link to Antibody to human parvovirus in outbreak of erythema infectiosum in Japan.
  309. Comparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S. Prince AM, Brotman B, Purcell RH, Gerin JL. A final report on safety and immunogenicity of a bivalent aqueous subunit HBV vaccine.  J. Med. Virol.  1985;15;4  Link to A final report on safety and immunogenicity of a bivalent aqueous subunit HBV vaccine.
  310. Journal Article Baroudy BM, Ticehurst JR, Miele TA, Maizel JV, Purcell RH, Feinstone SM. Sequence analysis of hepatitis A virus cDNA coding for capsid proteins and RNA polymerase.  Proc. Natl. Acad. Sci. U.S.A.  1985;82;7  Link to Sequence analysis of hepatitis A virus cDNA coding for capsid proteins and RNA polymerase.
  311. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Ljunggren KE, Patarroyo ME, Engle R, Purcell RH, Gerin JL. Viral hepatitis in Colombia: a study of the "hepatitis of the Sierra Nevada de Santa Marta".  Hepatology  1985;5;2  Link to Viral hepatitis in Colombia: a study of the "hepatitis of the Sierra Nevada de Santa Marta".
  312. In VitroJournal Article Shiraishi H, Alter HJ, Feinstone SM, Purcell RH. Rheumatoid factor-like reactants in sera proven to transmit non-A, non-B hepatitis: a potential source of false-positive reactions in non-A, non-B assays.  Hepatology  1985;5;2  Link to Rheumatoid factor-like reactants in sera proven to transmit non-A, non-B hepatitis: a potential source of false-positive reactions in non-A, non-B assays.
  313. Journal Article Purcell RH, Gerin JL. Prospects for second and third generation hepatitis B vaccines.  Hepatology  1985;5;1  Link to Prospects for second and third generation hepatitis B vaccines.
  314. 1984

  315. Journal Article Ponzetto A, Seeff LB, Buskell-Bales Z, Ishak KG, Hoofnagle JH, Zimmerman HJ, Purcell RH, Gerin JL. Hepatitis B markers in United States drug addicts with special emphasis on the delta hepatitis virus.  Hepatology  1984;4;6  Link to Hepatitis B markers in United States drug addicts with special emphasis on the delta hepatitis virus.
  316. Journal ArticleReview Purcell RH, Rizzetto M, Gerin JL. Hepatitis delta virus infection of the liver.  Semin. Liver Dis.  1984;4;4  Link to Hepatitis delta virus infection of the liver.
  317. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Ponzetto A, Cote PJ, Ford EC, Purcell RH, Gerin JL. Core antigen and antibody in woodchucks after infection with woodchuck hepatitis virus.  J. Virol.  1984;52;1  Link to Core antigen and antibody in woodchucks after infection with woodchuck hepatitis virus.
  318. Journal Article Cupps TR, Gerin JL, Purcell RH, Goldsmith PK, Fauci AS. In vitro antigen-induced antibody responses to hepatitis B surface antigen in man. Kinetic and cellular requirements.  J. Clin. Invest.  1984;74;4  Link to In vitro antigen-induced antibody responses to hepatitis B surface antigen in man. Kinetic and cellular requirements.
  319. Journal Article Moss B, Smith GL, Gerin JL, Purcell RH. Live recombinant vaccinia virus protects chimpanzees against hepatitis B.  Nature  1984;311;5981  Link to Live recombinant vaccinia virus protects chimpanzees against hepatitis B.
  320. Journal Article Hanson RG, Hoofnagle JH, Minuk GY, Purcell RH, Gerin JL. Cell-mediated immunity to hepatitis B surface antigen in man.  Clin. Exp. Immunol.  1984;57;2  Link to Cell-mediated immunity to hepatitis B surface antigen in man.
  321. Journal Article Cupps TR, Goldsmith PK, Volkman DJ, Gerin JL, Purcell RH, Fauci AS. Activation of human peripheral blood B cells following immunization with hepatitis B surface antigen vaccine.  Cell. Immunol.  1984;86;1  Link to Activation of human peripheral blood B cells following immunization with hepatitis B surface antigen vaccine.
  322. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Ponzetto A, Cote PJ, Popper H, Hoyer BH, London WT, Ford EC, Bonino F, Purcell RH, Gerin JL. Transmission of the hepatitis B virus-associated delta agent to the eastern woodchuck.  Proc. Natl. Acad. Sci. U.S.A.  1984;81;7  Link to Transmission of the hepatitis B virus-associated delta agent to the eastern woodchuck.
  323. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Bonino F, Hoyer B, Shih JW, Rizzetto M, Purcell RH, Gerin JL. Delta hepatitis agent: structural and antigenic properties of the delta-associated particle.  Infect. Immun.  1984;43;3  Link to Delta hepatitis agent: structural and antigenic properties of the delta-associated particle.
  324. Journal Article Canese MG, Rizzetto M, Novara R, London WT, Purcell RH. Experimental infection of chimpanzees with the HBsAg-associated delta (delta) agent: an ultrastructural study.  J. Med. Virol.  1984;13;1  Link to Experimental infection of chimpanzees with the HBsAg-associated delta (delta) agent: an ultrastructural study.
  325. 1983

  326. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Ticehurst JR, Racaniello VR, Baroudy BM, Baltimore D, Purcell RH, Feinstone SM. Molecular cloning and characterization of hepatitis A virus cDNA.  Proc. Natl. Acad. Sci. U.S.A.  1983;80;19  Link to Molecular cloning and characterization of hepatitis A virus cDNA.
  327. Comparative StudyJournal Article Kamimura T, Ponzetto A, Bonino F, Feinstone SM, Gerin JL, Purcell RH. Cytoplasmic tubular structures in liver of HBsAg carrier chimpanzees infected with delta agent and comparison with cytoplasmic structures in non-A, non-B hepatitis.  Hepatology  1983;3;5  Link to Cytoplasmic tubular structures in liver of HBsAg carrier chimpanzees infected with delta agent and comparison with cytoplasmic structures in non-A, non-B hepatitis.
  328. Journal Article Minuk GY, Hoofnagle JH, McAuliffe VJ, Purcell RH. IgM antibody responses to hepatitis B surface antigen in recipients of hepatitis B virus vaccine.  J. Infect. Dis.  1983;148;2  Link to IgM antibody responses to hepatitis B surface antigen in recipients of hepatitis B virus vaccine.
  329. Comparative StudyJournal Article Feinstone SM, Mihalik KB, Kamimura T, Alter HJ, London WT, Purcell RH. Inactivation of hepatitis B virus and non-A, non-B hepatitis by chloroform.  Infect. Immun.  1983;41;2  Link to Inactivation of hepatitis B virus and non-A, non-B hepatitis by chloroform.
  330. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Gerin JL, Alexander H, Shih JW, Purcell RH, Dapolito G, Engle R, Green N, Sutcliffe JG, Shinnick TM, Lerner RA. Chemically synthesized peptides of hepatitis B surface antigen duplicate the d/y specificities and induce subtype-specific antibodies in chimpanzees.  Proc. Natl. Acad. Sci. U.S.A.  1983;80;8  Link to Chemically synthesized peptides of hepatitis B surface antigen duplicate the d/y specificities and induce subtype-specific antibodies in chimpanzees.
  331. Journal Article Flores J, Boeggeman E, Purcell RH, Sereno M, Perez I, White L, Wyatt RG, Chanock RM, Kapikian AZ. A dot hybridisation assay for detection of rotavirus.  Lancet  1983;1;8324  Link to A dot hybridisation assay for detection of rotavirus.
  332. Journal Article Mortimer PP, Humphries RK, Moore JG, Purcell RH, Young NS. A human parvovirus-like virus inhibits haematopoietic colony formation in vitro.  Nature  1983;302;5907  Link to A human parvovirus-like virus inhibits haematopoietic colony formation in vitro.
  333. Journal Article Tabor E, Purcell RH, London WT, Gerety RJ. Use of and interpretation of results using inocula of hepatitis B virus with known infectivity titers.  J. Infect. Dis.  1983;147;3  Link to Use of and interpretation of results using inocula of hepatitis B virus with known infectivity titers.
  334. Journal Article Wen YM, Mitamura K, Merchant B, Tang ZY, Purcell RH. Nuclear antigen detected in hepatoma cell lines containing integrated hepatitis B virus DNA.  Infect. Immun.  1983;39;3  Link to Nuclear antigen detected in hepatoma cell lines containing integrated hepatitis B virus DNA.
  335. 1982

  336. Comparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S. Koff RS, Pannuti CS, Pereira ML, Hansson BG, Dienstag JL, Neto VA, Wong DC, Purcell RH. Hepatitis A and non-A, non-B viral hepatitis in São Paulo, Brazil: epidemiological, clinical and laboratory comparisons in hospitalized patients.  Hepatology  1982;2;4  Link to Hepatitis A and non-A, non-B viral hepatitis in São Paulo, Brazil: epidemiological, clinical and laboratory comparisons in hospitalized patients.
  337. 1981

  338. Journal Article Feinstone SM, Alter HJ, Dienes HP, Shimizu Y, Popper H, Blackmore D, Sly D, London WT, Purcell RH. Non-A, non-B hepatitis in chimpanzees and marmosets.  J. Infect. Dis.  1981;144;6  Link to Non-A, non-B hepatitis in chimpanzees and marmosets.
  339. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Thung SN, Gerber MA, Purcell RH, London WT, Mihalik KB, Popper H. Animal model of human disease. Chimpanzee carriers of hepatitis B virus. Chimpanzee hepatitis B carriers.  Am. J. Pathol.  1981;105;3  Link to Animal model of human disease. Chimpanzee carriers of hepatitis B virus. Chimpanzee hepatitis B carriers.
  340. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Rizzetto M, Canese MG, Purcell RH, London WT, Sly LD, Gerin JL. Experimental HBV and delta infections of chimpanzees: occurrence and significance of intrahepatic immune complexes of HBcAg and delta antigen.  Hepatology  1981;1;6  Link to Experimental HBV and delta infections of chimpanzees: occurrence and significance of intrahepatic immune complexes of HBcAg and delta antigen.
  341. Journal Article Alter HJ, Purcell RH, Holland PV, Alling DW, Koziol DE. Donor transaminase and recipient hepatitis. Impact on blood transfusion services.  JAMA  1981;246;6  Link to Donor transaminase and recipient hepatitis. Impact on blood transfusion services.
  342. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Daemer RJ, Feinstone SM, Gust ID, Purcell RH. Propagation of human hepatitis A virus in African green monkey kidney cell culture: primary isolation and serial passage.  Infect. Immun.  1981;32;1  Link to Propagation of human hepatitis A virus in African green monkey kidney cell culture: primary isolation and serial passage.
  343. Case ReportsJournal ArticleResearch Support, U.S. Gov't, P.H.S. Bonino F, Hoyer B, Ford E, Shih JW, Purcell RH, Gerin JL. The delta agent: HBsAg particles with delta antigen and RNA in the serum of an HBV carrier.  Hepatology  1981;1;2  Link to The delta agent: HBsAg particles with delta antigen and RNA in the serum of an HBV carrier.
  344. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Popper H, Shih JW, Gerin JL, Wong DC, Hoyer BH, London WT, Sly DL, Purcell RH. Woodchuck hepatitis and hepatocellular carcinoma: correlation of histologic with virologic observations.  Hepatology  1981;1;2  Link to Woodchuck hepatitis and hepatocellular carcinoma: correlation of histologic with virologic observations.
  345. Journal ArticleReview Krugman S, McAuliffe VJ, Purcell RH. Hepatitis B vaccines: present status.  Semin. Liver Dis.  1981;1;1  Link to Hepatitis B vaccines: present status.
  346. Clinical TrialControlled Clinical TrialJournal ArticleResearch Support, U.S. Gov't, P.H.S. Dienstag JL, Krotoski WA, Howard WA, Purcell RH, Neva FA, Galambos JT, Glew RH. Non-A, non-B hepatitis after experimental transmission of malaria by inoculation of blood.  J. Infect. Dis.  1981;143;2  Link to Non-A, non-B hepatitis after experimental transmission of malaria by inoculation of blood.
  347. Journal Article Hansson BG, Calhoun JK, Wong DC, Feinstone SM, Purcell RH, Pannuti CS, Pereira JL, Koff RS, Dienstag JL, Iwarson S. Serodiagnosis of viral hepatitis A by a solid-phase radioimmunoassay specific for IgM antibodies.  Scand. J. Infect. Dis.  1981;13;1  Link to Serodiagnosis of viral hepatitis A by a solid-phase radioimmunoassay specific for IgM antibodies.
  348. 1980

  349. Journal Article Daemer RJ, Feinstone SM, Alexander JJ, Tully JG, London WT, Wong DC, Purcell RH. PLC/PRF/5 (Alexander) hepatoma cell line: further characterization and studies of infectivity.  Infect. Immun.  1980;30;2  Link to PLC/PRF/5 (Alexander) hepatoma cell line: further characterization and studies of infectivity.
  350. Journal Article Wong DC, Purcell RH, Sreenivasan MA, Prasad SR, Pavri KM. Epidemic and endemic hepatitis in India: evidence for a non-A, non-B hepatitis virus aetiology.  Lancet  1980;2;8200  Link to Epidemic and endemic hepatitis in India: evidence for a non-A, non-B hepatitis virus aetiology.
  351. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Rizzetto M, Hoyer B, Canese MG, Shih JW, Purcell RH, Gerin JL. delta Agent: association of delta antigen with hepatitis B surface antigen and RNA in serum of delta-infected chimpanzees.  Proc. Natl. Acad. Sci. U.S.A.  1980;77;10  Link to delta Agent: association of delta antigen with hepatitis B surface antigen and RNA in serum of delta-infected chimpanzees.
  352. Comparative StudyJournal Article Rizzetto M, Purcell RH, Gerin JL. Epidemiology of HBV-associated delta agent: geographical distribution of anti-delta and prevalence in polytransfused HBsAg carriers.  Lancet  1980;1;8180  Link to Epidemiology of HBV-associated delta agent: geographical distribution of anti-delta and prevalence in polytransfused HBsAg carriers.
  353. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Rizzetto M, Canese MG, Gerin JL, London WT, Sly DL, Purcell RH. Transmission of the hepatitis B virus-associated delta antigen to chimpanzees.  J. Infect. Dis.  1980;141;5  Link to Transmission of the hepatitis B virus-associated delta antigen to chimpanzees.
  354. Journal ArticleResearch Support, U.S. Gov't, P.H.S.Review McAuliffe VJ, Purcell RH, Gerin JL. Type B hepatitis: a review of current prospects for a safe and effective vaccine.  Rev. Infect. Dis.  1980;2;3  Link to Type B hepatitis: a review of current prospects for a safe and effective vaccine.
  355. Journal Article Feinstone SM, Purcell RH. New methods for the serodiagnosis of hepatitis A.  Gastroenterology  1980;78;5 Pt 1  Link to New methods for the serodiagnosis of hepatitis A.
  356. Journal Article Mathiesen LR, Møller AM, Purcell RH, London WT, Feinstone SM. Hepatitis A virus in the liver and intestine of marmosets after oral inoculation.  Infect. Immun.  1980;28;1  Link to Hepatitis A virus in the liver and intestine of marmosets after oral inoculation.
  357. Comparative StudyJournal Article Gust ID, Feinstone SM, Purcell RH, Alter HJ. Detection of antibodies to single-stranded DNA in naturally acquired and experimentally induced viral hepatitis.  J. Med. Virol.  1980;6;1  Link to Detection of antibodies to single-stranded DNA in naturally acquired and experimentally induced viral hepatitis.
  358. Journal Article Mathiesen LR, Skinoj P, Nielsen JO, Purcell RH, Wong D, Ranek L. Hepatitis type A, B, and non-A non-B in fulminant hepatitis.  Gut  1980;21;1  Link to Hepatitis type A, B, and non-A non-B in fulminant hepatitis.
  359. Journal Article Mathiesen LR, Hardt F, Dietrichson O, Purcell RH, Wong D, Skinhøj P, Nielsen JO, Zoffmann H, Iversen K. The role of acute hepatitis type A, B, and non-A non-B in the development of chronic active liver disease.  Scand. J. Gastroenterol.  1980;15;1  Link to The role of acute hepatitis type A, B, and non-A non-B in the development of chronic active liver disease.
  360. 1979

  361. Journal Article Rizzetto M, Shih JW, Gocke DJ, Purcell RH, Verme G, Gerin JL. Incidence and significance of antibodies to delta antigen in hepatitis B virus infection.  Lancet  1979;2;8150  Link to Incidence and significance of antibodies to delta antigen in hepatitis B virus infection.
  362. Journal Article Hansson BG, Purcell RH. Sites that bind polymerized albumin on hepatitis B surface antigen particles: detection by radioimmunoassay.  Infect. Immun.  1979;26;1  Link to Sites that bind polymerized albumin on hepatitis B surface antigen particles: detection by radioimmunoassay.
  363. Congresses Gerety RJ, Tabor E, Purcell RH, Tyeryar FJ. Summary of an international workshop on hepatitis B vaccines.  J. Infect. Dis.  1979;140;4  Link to Summary of an international workshop on hepatitis B vaccines.
  364. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Routenberg JA, Dienstag JL, Harrison WO, Kilpatrick ME, Hooper RR, Chisari FV, Purcell RH, Fornes MF. Foodborne outbreak of hepatitis A: clinical and laboratory features of acute and protracted illness.  Am. J. Med. Sci.  1979;278;2  Link to Foodborne outbreak of hepatitis A: clinical and laboratory features of acute and protracted illness.
  365. Journal Article Wong DC, Purcell RH, Rosen L. Prevalence of antibody to hepatitis A and hepatitis B viruses in selected populations of the South Pacific.  Am. J. Epidemiol.  1979;110;3  Link to Prevalence of antibody to hepatitis A and hepatitis B viruses in selected populations of the South Pacific.
  366. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Shimizu YK, Feinstone SM, Purcell RH, Alter HJ, London WT. Non-A, non-B hepatitis: ultrastructural evidence for two agents in experimentally infected chimpanzees.  Science  1979;205;4402  Link to Non-A, non-B hepatitis: ultrastructural evidence for two agents in experimentally infected chimpanzees.
  367. Journal Article Berman M, Alter HJ, Ishak KG, Purcell RH, Jones EA. The chronic sequelae of non-A, non-B hepatitis.  Ann. Intern. Med.  1979;91;1  Link to The chronic sequelae of non-A, non-B hepatitis.
  368. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Dienstag JL, Bhan AK, Alter HJ, Feinstone SM, Purcell RH. Circulating immune complexes in non-A, non-B hepatitis. Possible masking of viral antigen.  Lancet  1979;1;8129  Link to Circulating immune complexes in non-A, non-B hepatitis. Possible masking of viral antigen.
  369. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Galbraith RM, Dienstag JL, Purcell RH, Gower PH, Zuckerman AJ, Williams R. Non-A non-B hepatitis associated with chronic liver disease in a haemodialysis unit.  Lancet  1979;1;8123  Link to Non-A non-B hepatitis associated with chronic liver disease in a haemodialysis unit.
  370. Journal Article Wankya BM, Hansen DP, Ngindu AM, Feinstone SF, Purcell RH. Seroepidemiology of hepatitis A and B in Kenya. A rural population survey in Machakos District.  East Afr Med J  1979;56;3  Link to Seroepidemiology of hepatitis A and B in Kenya. A rural population survey in Machakos District.
  371. Journal Article Mathiesen LR, Skinhøj P, Hardt F, Nielsen JO, Sloth K, Zoffmann H, Møller AM, Wong D, Purcell RH. Epidemiology and clinical characteristics of acute hepatitis types A, B, and non-A non-B.  Scand. J. Gastroenterol.  1979;14;7  Link to Epidemiology and clinical characteristics of acute hepatitis types A, B, and non-A non-B.
  372. 1978

  373. Journal Article Shimizu YK, Mathiesen LR, Lorenz D, Drucker J, Feinstone SM, Wagner JA, Purcell RH. Localization of hepatitis A antigen in liver tissue by peroxidase-conjugated antibody method: light and electron microscopic studies.  J. Immunol.  1978;121;5  Link to Localization of hepatitis A antigen in liver tissue by peroxidase-conjugated antibody method: light and electron microscopic studies.
  374. Editorial Feinstone SM, Purcell RH. Non-A, non-B hepatitis.  JAMA  1978;240;13  Link to Non-A, non-B hepatitis.
  375. Journal Article Mathiesen LR, Drucker J, Lorenz D, Wagner JA, Gerety RJ, Purcell RH. Localization of hepatitis A antigen in marmoset organs during acute infection with hepatitis A virus.  J. Infect. Dis.  1978;138;3  Link to Localization of hepatitis A antigen in marmoset organs during acute infection with hepatitis A virus.
  376. Journal Article Murphy BL, Maynard JE, Bradley DW, Ebert JW, Mathiesen LR, Purcell RH. Immunofluorescence of hepatitis A virus antigen in chimpanzees.  Infect. Immun.  1978;21;2  Link to Immunofluorescence of hepatitis A virus antigen in chimpanzees.
  377. Journal Article Purcell RH. The viral hepatitides.  Hosp Pract  1978;13;7  Link to The viral hepatitides.
  378. Journal ArticleReview Purcell RH, Gerin JL. Hepatitis B vaccines. On the threshold.  Am. J. Clin. Pathol.  1978;70;1 Suppl  Link to Hepatitis B vaccines. On the threshold.
  379. Journal Article Hess G, Wagner J, Arnold W, Purcell RH, Meyer zum Büschenfelde KH. Anti-HBc titers in HBeAg and anti-HBe positive asymptomatic HBsAg carriers.  Z Immunitatsforsch Immunobiol  1978;154;3  Link to Anti-HBc titers in HBeAg and anti-HBe positive asymptomatic HBsAg carriers.
  380. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Stevens CE, Silbert JA, Miller DR, Dienstag JL, Purcell RH, Szmuness W. Serologic evidence of hepatitis A and B virus infections in thalassemia patients: a retrospective study.  Transfusion  1978;18;3  Link to Serologic evidence of hepatitis A and B virus infections in thalassemia patients: a retrospective study.
  381. Journal Article Arnold W, Hess G, Purcell RH, Kaplan PM, Gerin JL, Meyer KH. Anti-HBc, HBeAg and DNApolymerase activity in healthy HBsAg carriers and patients with inflammatory liver diseases.  Klin. Wochenschr.  1978;56;6  Link to Anti-HBc, HBeAg and DNApolymerase activity in healthy HBsAg carriers and patients with inflammatory liver diseases.
  382. Journal Article Alter HJ, Purcell RH, Holland PV, Popper H. Transmissible agent in non-A, non-B hepatitis.  Lancet  1978;1;8062  Link to Transmissible agent in non-A, non-B hepatitis.
  383. Clinical TrialJournal ArticleRandomized Controlled Trial Seeff LB, Wright EC, Zimmerman HJ, Alter HJ, Dietz AA, Felsher BF, Finkelstein JD, Garcia-Pont P, Gerin JL, Greenlee HB, Hamilton J, Holland PV, Kaplan PM, Kiernan T, Koff RS, Leevy CM, McAuliffe VJ, Nath N, Purcell RH, Schiff ER, Schwartz CC, Tamburro CH, Vlahcevic Z, Zemel R, Zimmon DS. Type B hepatitis after needle-stick exposure: prevention with hepatitis B immune globulin. Final report of the Veterans Administration Cooperative Study.  Ann. Intern. Med.  1978;88;3  Link to Type B hepatitis after needle-stick exposure: prevention with hepatitis B immune globulin. Final report of the Veterans Administration Cooperative Study.
  384. Journal ArticleResearch Support, U.S. Gov't, P.H.S.Review Dienstag JL, Szmuness W, Stevens CE, Purcell RH. Hepatitis A virus infection: new insights from seroepidemiologic studies.  J. Infect. Dis.  1978;137;3  Link to Hepatitis A virus infection: new insights from seroepidemiologic studies.
  385. Journal Article Gerin JL, Wai-Kuo Shih J, McAuliffe VJ, Purcell RH. Antigens of hepatitis B virus: failure to detect HBeAg on the surfaces of HBsAg forms.  J. Gen. Virol.  1978;38;3  Link to Antigens of hepatitis B virus: failure to detect HBeAg on the surfaces of HBsAg forms.
  386. Journal ArticleReview Feinstone SM, Purcell RH. Non-A, non-B hepatitis.  Annu. Rev. Med.  1978;29  Link to Non-A, non-B hepatitis.
  387. 1977

  388. Journal Article Barker LF, Dienstag JL, Lorenz DE, Purcell RH, Wong DC, Feinstone SM, Peterson MR, Rosen MW. Serologic and animal inoculation studies of a communal outbreak of viral hepatitis, type A.  Am. J. Med. Sci.  1977;274;3  Link to Serologic and animal inoculation studies of a communal outbreak of viral hepatitis, type A.
  389. Journal Article Mathiesen LR, Feinstone SM, Purcell RH, Wagner JA. Detection of hepatitis A antigen by immunofluorescence.  Infect. Immun.  1977;18;2  Link to Detection of hepatitis A antigen by immunofluorescence.
  390. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Szmuness W, Dienstag JL, Purcell RH, Stevens CE, Wong DC, Ikram H, Bar-Shany S, Beasley RP, Desmyter J, Gaon JA. The prevalence of antibody to hepatitis A antigen in various parts of the world: a pilot study.  Am. J. Epidemiol.  1977;106;5  Link to The prevalence of antibody to hepatitis A antigen in various parts of the world: a pilot study.
  391. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Stevens CE, Cherubin CE, Dienstag JL, Purcell RH, Szmuness W. Antibody to hepatitis A antigen in children.  J. Pediatr.  1977;91;3  Link to Antibody to hepatitis A antigen in children.
  392. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Arnold GH, Shih JW, Kaplan PM, Purcell RH, Gerin JL, Bueschenfelde KH. Expression of hepatitis B virus-specific markers in asymptomatic hepatitis B surface antigen carriers.  Infect. Immun.  1977;17;3  Link to Expression of hepatitis B virus-specific markers in asymptomatic hepatitis B surface antigen carriers.
  393. Case ReportsJournal Article Peters CJ, Reeves WC, Purcell RH. Disparate response of monozygotic twins to hepatitis B virus infection.  J. Pediatr.  1977;91;2  Link to Disparate response of monozygotic twins to hepatitis B virus infection.
  394. Journal Article Hoofnagle JH, Gerety RJ, Tabor E, Feinstone SM, Barker LF, Purcell RH. Transmission of non-A, non-B hepatitis.  Ann. Intern. Med.  1977;87;1  Link to Transmission of non-A, non-B hepatitis.
  395. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Szmuness W, Dienstag JL, Purcell RH, Prince AM, Stevens CE, Levine RW. Hepatitis type A and hemodialysis: a seroepidemiologic study in 15 U.S. centers.  Ann. Intern. Med.  1977;87;1  Link to Hepatitis type A and hemodialysis: a seroepidemiologic study in 15 U.S. centers.
  396. Journal Article Dienstag JL, Alaama A, Mosley JW, Redeker AG, Purcell RH. Etiology of sporadic hepatitis B surface antigen-negative hepatitis.  Ann. Intern. Med.  1977;87;1  Link to Etiology of sporadic hepatitis B surface antigen-negative hepatitis.
  397. Journal Article Dienstag JL, Purcell RH. Hepatitis A antigen: clinical implications.  Compr Ther  1977;3;7  Link to Hepatitis A antigen: clinical implications.
  398. Journal ArticleReview Dienstag JL, Purcell RH. Recent advances in the identification of hepatitis viruses.  Postgrad Med J  1977;53;621  Link to Recent advances in the identification of hepatitis viruses.
  399. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Meyers JD, Dienstag JL, Purcell RH, Thomas ED, Holmes KK. Parenterally transmitted non-A, non-B hepatitis: an epidemic reassessed.  Ann. Intern. Med.  1977;87;1  Link to Parenterally transmitted non-A, non-B hepatitis: an epidemic reassessed.
  400. Journal Article Alter HJ, Purcell RH, Gerin JL, London WT, Kaplan PM, McAuliffe VJ, Wagner J, Holland PV. Transmission of hepatitis B to chimpanzees by hepatitis B surface antigen-positive saliva and semen.  Infect. Immun.  1977;16;3  Link to Transmission of hepatitis B to chimpanzees by hepatitis B surface antigen-positive saliva and semen.
  401. Comparative StudyJournal ArticleResearch Support, U.S. Gov't, P.H.S. Szmuness W, Purcell RH, Dienstag JL, Stevens CE. Antibody to hepatitis A antigen in institutionalized mentally retarded patients.  JAMA  1977;237;16  Link to Antibody to hepatitis A antigen in institutionalized mentally retarded patients.
  402. Comparative StudyJournal Article Kalica AR, Purcell RH, Sereno MM, Wyatt RG, Kim HW, Chanock RM, Kapikian AZ. A microtiter solid phase radioimmunoassay for detection of the human reovirus-like agent in stools.  J. Immunol.  1977;118;4  Link to A microtiter solid phase radioimmunoassay  for detection of the human reovirus-like agent in stools.
  403. Clinical TrialComparative StudyJournal Article Schaffner F, Dienstag JL, Purcell RH, Popper H. Chimpanzee livers after infection with human hepatitis viruses A and B: Ultrastructural studies.  Arch. Pathol. Lab. Med.  1977;101;3  Link to Chimpanzee livers after infection with human hepatitis viruses A and B: Ultrastructural studies.
  404. Journal Article Gust ID, Dienstag JL, Purcell RH, Lucas CR. Non-B hepatitis in Melbourne: a serological study of hepatitis A virus infection.  Br Med J  1977;1;6055  Link to Non-B hepatitis in Melbourne: a serological study of hepatitis A virus infection.
  405. Journal Article Mosley JW, Redeker AG, Feinstone SM, Purcell RH. Mutliple hepatitis viruses in multiple attacks of acute viral hepatitis.  N. Engl. J. Med.  1977;296;2  Link to Mutliple hepatitis viruses in multiple attacks of acute viral hepatitis.
  406. 1976

  407. Journal Article Dienstag JL, Wagner JA, Purcell RH, London WT, Lorenz DE. Virus-like particles and GB agent hepatitis.  Nature  1976;264;5583  Link to Virus-like particles and GB agent hepatitis.
  408. Journal Article Alter HJ, Seeff LB, Kaplan PM, McAuliffe VJ, Wright EC, Gerin JL, Purcell RH, Holland PV, Zimmerman HJ. Type B hepatitis: the infectivity of blood positive for e antigen and DNA polymerase after accidental needlestick exposure.  N. Engl. J. Med.  1976;295;17  Link to Type B hepatitis: the infectivity of blood positive for e antigen and DNA polymerase after accidental needlestick exposure.
  409. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Purcell RH, London WT, McAuliffe VJ, Palmer AE, Kaplan PM, Gerin JL, Wagner J, Popper H, Lvovsky E, Wong DC, Levy HB. Modification of chronic hepatitis-B virus infection in chimpanzees by administration of an interferon inducer.  Lancet  1976;2;7989  Link to Modification of chronic hepatitis-B virus infection in chimpanzees by administration of an interferon inducer.
  410. Comparative StudyJournal Article Dienstag JL, Popper H, Purcell RH. The pathology of viral hepatitis types A and B in chimpanzees. A comparison.  Am. J. Pathol.  1976;85;1  Link to The pathology of viral hepatitis types A and B in chimpanzees. A comparison.
  411. Comparative StudyJournal Article Dienstag JL, Krugman S, Wong DC, Purcell RH. Comparison of serological tests for antibody to hepatitis A antigen, using coded specimens from individuals infected with the MS-1 strain of hepatitis A virus.  Infect. Immun.  1976;14;4  Link to Comparison of serological tests for antibody to hepatitis A antigen, using coded specimens from individuals infected with the MS-1 strain of hepatitis A virus.
  412. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Gold JW, Shih JW, Purcell RH, Gerin JL. Characterization of antibodies to the structural polypeptides of HGSAg: evidence for subtype-specific determinants.  J. Immunol.  1976;117;4  Link to Characterization of antibodies to the structural polypeptides of HGSAg: evidence for subtype-specific determinants.
  413. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Szmuness W, Dienstag JL, Purcell RH, Harley EJ, Stevens CE, Wong DC. Distribution of antibody to hepatitis a antigen in urban adult populations.  N. Engl. J. Med.  1976;295;14  Link to Distribution of antibody to hepatitis a antigen in urban adult populations.
  414. Journal Article Dienstag JL, Schulman AN, Gerety RJ, Hoofnagle JH, Lorenz DE, Purcell RH, Barker LF. Hepatitis A antigen isolated from liver and stool: immunologic comparison of antisera prepared in guinea pigs.  J. Immunol.  1976;117;3  Link to Hepatitis A antigen isolated from liver and stool: immunologic comparison of antisera prepared in guinea pigs.
  415. Journal Article Peters CJ, Purcell RH, Lander JJ, Johnson KM. Radioimmunoassay for antibody to hepatitis B surface antigen shows transmission of hepatitis B virus among household contacts.  J. Infect. Dis.  1976;134;3  Link to Radioimmunoassay for antibody to hepatitis B surface antigen shows transmission of hepatitis B virus among household contacts.
  416. Journal Article Dienstag JL, Davenport FM, McCollum RW, Hennessy AV, Klatskin G, Purcell RH. Nonhuman primate-associated viral hepatitis type A. Serologic evidence of hepatitis A virus infection.  JAMA  1976;236;5  Link to Nonhuman primate-associated viral hepatitis type A. Serologic evidence of hepatitis A virus infection.
  417. Journal Article Sever JL, Kapikian AZ, Finestone S, Purcell RH, Gilkeson MR. Hepatitis A and Down's syndrome: lack of an association.  J. Infect. Dis.  1976;134;2  Link to Hepatitis A and Down's syndrome: lack of an association.
  418. Journal Article Schulman AN, Dienstag JL, Jackson DR, Hoofnagle JH, Gerety RJ, Purcell RH, Barker LF. Hepatitis A antigen particles in liver, bile, and stool of chimpanzees.  J. Infect. Dis.  1976;134;1  Link to Hepatitis A antigen particles in liver, bile, and stool of chimpanzees.
  419. Journal Article Dienstag JL, Alling DW, Purcell RH. Quantitation of antibody to hepatitis A antigen by immune electron microscopy.  Infect. Immun.  1976;13;4  Link to Quantitation of antibody to hepatitis A antigen by immune electron microscopy.
  420. Journal Article McAuliffe VJ, Purcell RH, Le Bouvier GL. Editorial: e: a third hepatitis B antigen?  N. Engl. J. Med.  1976;294;14  Link to Editorial: e: a third hepatitis B antigen?
  421. Journal Article Dienstag JL, Gust ID, Lucas CR, Wong DC, Purcell RH. Mussel-associated viral hepatitis, type A: serological confirmation.  Lancet  1976;1;7959  Link to Mussel-associated viral hepatitis, type A: serological confirmation.
  422. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Kaplan PM, Ford EC, Purcell RH, Gerin JL. Demonstration of subpopulations of Dane particles.  J. Virol.  1976;17;3  Link to Demonstration of subpopulations of Dane particles.
  423. In VitroJournal Article Moritsugu Y, Dienstag JL, Valdesuso J, Wong DC, Wagner J, Routenberg JA, Purcell RH. Purification of hepatitis A antigen from feces and detection of antigen and antibody by immune adherence hemagglutination.  Infect. Immun.  1976;13;3  Link to Purification of hepatitis A antigen from feces and detection of antigen and antibody by immune adherence hemagglutination.
  424. Journal Article Purcell RH, Wong DC, Moritsugu Y, Dienstag JL, Routenberg JA, Boggs JD. A microtiter solid-phase radioimmunoassay for hepatitis A antigen and antibody.  J. Immunol.  1976;116;2  Link to A microtiter solid-phase radioimmunoassay for hepatitis A antigen and antibody.
  425. Journal Article Dietz WH, Porcell O, Moon TE, Peters CJ, Purcell RH. IgM levels and IgM-mediated immune responses in patients with acute hepatitis A, acute hepatitis B and chronic HB antigenaemia.  Clin. Exp. Immunol.  1976;23;1  Link to IgM levels and IgM-mediated immune responses in patients with acute hepatitis A, acute hepatitis B and chronic HB antigenaemia.
  426. Journal Article Madden DL, Matthew EB, Dietzman DE, Purcell RH, Sever JL, Rostafinski M, Mata A. Hepatitis and Down's syndrome.  Am J Ment Defic  1976;80;4  Link to Hepatitis and Down's syndrome.
  427. Journal Article Madden DL, Dietzman DE, Matthew EB, Sever JL, Lander JJ, Purcell RH, Rostafinski M, Mata A. Epidemiology of hepatitis B virus in an institution for mentally retarded persons.  Am J Ment Defic  1976;80;4  Link to Epidemiology of hepatitis B virus in an institution for mentally retarded persons.
  428. Journal Article Murphy BL, Peterson JM, Smith JL, Gitnick GL, Auslander MO, Berquist KR, Maynard JE, Purcell RH. Correlation between fluorescent antibody detection of hepatitis B core antigen in liver biopsies and the presence of e antigen in serum.  Infect. Immun.  1976;13;1  Link to Correlation between fluorescent antibody detection of hepatitis B core antigen in liver biopsies and the presence of e antigen in serum.
  429. 1975

  430. Journal Article Gerin JL, Ford EC, Purcell RH. Biochemical characterization of Australia antigen. Evidence for defective particles of hepatitis B virus.  Am. J. Pathol.  1975;81;3  Link to Biochemical characterization of Australia antigen. Evidence for defective particles of hepatitis B virus.
  431. Journal Article Dienstag JL, Feinstone SM, Purcell RH, Hoofnagle JH, Barker LF, London WT, Popper H, Peterson JM, Kapikian AZ. Experimental infection of chimpanzees with hepatitis A virus.  J. Infect. Dis.  1975;132;5  Link to Experimental infection of chimpanzees with hepatitis A virus.
  432. Journal Article Dienstag JL, Routenberg JA, Purcell RH, Hooper RR, Harrison WO. Foodhandler-associated outbreak of hepatitis type A. An immune electron microscopic study.  Ann. Intern. Med.  1975;83;5  Link to Foodhandler-associated outbreak of hepatitis type A. An immune electron microscopic study.
  433. Journal Article Alter HJ, Holland PV, Morrow AG, Purcell RH, Feinstone SM, Moritsugu Y. Clinical and serological analysis of transfusion-associated hepatitis.  Lancet  1975;2;7940  Link to Clinical and serological analysis of transfusion-associated hepatitis.
  434. Journal Article Barker LF, Maynard JE, Purcell RH, Hoofnagle JH, Berquist KR, London WT, Gerety RJ, Krushak DH. Hepatitis B virus infection in chimpanzees: titration of subtypes.  J. Infect. Dis.  1975;132;4  Link to Hepatitis B virus infection in chimpanzees: titration of subtypes.
  435. Journal Article Alter HJ, Holland PV, Purcell RH. The emerging pattern of post-transfusion hepatitis.  Am. J. Med. Sci.  1975;270;2  Link to The emerging pattern of post-transfusion hepatitis.
  436. Journal Article Berquist KR, Peterson JM, Murphy BL, Ebert JW, Maynard JE, Purcell RH. Hepatitis B antigens in serum and liver of chimpanzees acutely infected with hepatitis B virus.  Infect. Immun.  1975;12;3  Link to Hepatitis B antigens in serum and liver of chimpanzees acutely infected with hepatitis B virus.
  437. Journal Article Purcell RH, Gerin JL. Hepatitis B subunit vaccine: a preliminary report of safety and efficacy tests in chimpanzees.  Am. J. Med. Sci.  1975;270;2  Link to Hepatitis B subunit vaccine: a preliminary report of safety and efficacy tests in chimpanzees.
  438. Journal Article Barker LF, Maynard JE, Purcell RH, Hoofnagle JH, Berquist KR, London WT. Viral hepatitis, type B, in experimental animals.  Am. J. Med. Sci.  1975;270;1  Link to Viral hepatitis, type B, in experimental animals.
  439. Journal Article Maynard JE, Lorenz D, Bradley DW, Feinstone SM, Krushak DH, Barker LF, Purcell RH. Review of infectivity studies in nonhuman primates with virus-like particles associated with MS-1 hepatitis.  Am. J. Med. Sci.  1975;270;1  Link to Review of infectivity studies in nonhuman primates with virus-like particles associated with MS-1 hepatitis.
  440. Journal Article Purcell RH, Dienstag JL, Feinstone SM, Kapikian AZ. Relationship of hepatitis A antigen to viral hepatitis.  Am. J. Med. Sci.  1975;270;1  Link to Relationship of hepatitis A antigen to viral hepatitis.
  441. Journal Article Moritsugu Y, Gold JW, Wagner J, Dodd RY, Purcell RH. Hepatitis B core antigen. Detection of antibody by radioimmunoprecipitation.  J. Immunol.  1975;114;6  Link to Hepatitis B core antigen. Detection of antibody by radioimmunoprecipitation.
  442. Journal Article Feinstone SM, Kapikian AZ, Purcell RH, Alter HJ, Holland PV. Transfusion-associated hepatitis not due to viral hepatitis type A or B.  N. Engl. J. Med.  1975;292;15  Link to Transfusion-associated hepatitis not due to viral hepatitis type A or B.
  443. Journal Article Dienstag JL, Feinstone SM, Kapikian AZ, Purcell RH. Faecal shedding of hepatitis-A antigen.  Lancet  1975;1;7910  Link to Faecal shedding of hepatitis-A antigen.
  444. Journal Article Dienstag JL, Feinstone SM, Kapikian AZ, Purcell RH. Letter: Immune electron microscopy and hepatitis A.  Lancet  1975;1;7898  Link to Letter: Immune electron microscopy and hepatitis A.
  445. Journal ArticleResearch Support, U.S. Gov't, P.H.S. Reeves WC, Peters CJ, Moon TE, Purcell RH. Familial clustering of hepatitis B surface antigen among Panamanian Indians.  J. Infect. Dis.  1975;131;1  Link to Familial clustering of hepatitis B surface antigen among Panamanian Indians.
  446. Journal Article Murphy BL, Peterson JM, Ebert JW, Berquist KR, Maynard JE, Purcell RH. Immunofluorescent localization of hepatitis B antigens in chimpanzee tissues.  Intervirology  1975;6;4-5  Link to Immunofluorescent localization of hepatitis B antigens in chimpanzee tissues.
  447. Comparative StudyJournal Article Dienstag JL, Pelon W, Tyeryar F, Purcell RH. Serologic comparison of hepatitis A antigen to echovirus 25 isolate CR69(076) recovered from a patient with viral hepatitis.  Intervirology  1975;6;4-5  Link to Serologic comparison of hepatitis A antigen to echovirus 25 isolate CR69(076) recovered from a patient with viral hepatitis.
  448. 1974

  449. Journal Article Purcell RH. Viral hepatitis.  Prev Med  1974;3;4  Link to Viral hepatitis.
  450. Journal Article Alter HJ, Holland PV, Purcell RH. Viral hepatitis. Light at the end of the tunnel.  JAMA  1974;229;3  Link to Viral hepatitis. Light at the end of the tunnel.
  451. Journal Article Feinstone SM, Kapikian AZ, Gerin JL, Purcell RH. Buoyant density of the hepatitis A virus-like particle in cesium chloride.  J. Virol.  1974;13;6  Link to Buoyant density of the hepatitis A virus-like particle in cesium chloride.
  452. Journal Article Purcell RH. Hepatitis Research.  Science  1974;184;4132  Link to Hepatitis Research.
  453. Journal Article Gold JW, Alter HJ, Holland PV, Gerin JL, Purcell RH. Passive hemagglutination assay for antibody to subtypes of hepatitis B antigen.  J. Immunol.  1974;112;3  Link to Passive hemagglutination assay for antibody to subtypes of hepatitis B antigen.
  454. Journal Article Purcell RH, Gerin JL, Almeida JB, Holland PV. Radioimmunoassay for the detection of the core of the Dane particle and antibody to it.  Intervirology  1974;2;4  Link to Radioimmunoassay for the detection of the core of the Dane particle and antibody to it.
  455. 1973

  456. Comparative StudyJournal Article Alter HJ, Holland PV, Purcell RH, Gerin JL. The Ausria test: critical evaluation of sensitivity and specificity.  Blood  1973;42;6  Link to The Ausria test: critical evaluation of sensitivity and specificity.
  457. Journal Article Kaplan PM, Greenman RL, Gerin JL, Purcell RH, Robinson WS. DNA polymerase associated with human hepatitis B antigen.  J. Virol.  1973;12;5  Link to DNA polymerase associated with human hepatitis B antigen.
  458. Journal Article Lewis TL, Alter HJ, Chalmers TC, Holland PV, Purcell RH, Alling DW, Young D, Frenkel LD, Lee SL, Lamson ME. A comparison of the frequency of hepatitis-B antigen and antibody in hospital and nonhospital personnel.  N. Engl. J. Med.  1973;289;13  Link to A comparison of the frequency of hepatitis-B antigen and antibody in hospital and nonhospital personnel.
  459. Journal Article Reeves WC, Peters CJ, Lander JJ, Purcell RH, Johnson KM. Differences in the prevalence of hepatitis B antigen and antibody among Panamanian Indian populations.  J. Infect. Dis.  1973;128;3  Link to Differences in the prevalence of hepatitis B antigen and antibody among Panamanian Indian populations.
  460. 1972

  461. Journal Article Holland PV, Alter HJ, Purcell RH, Lander JJ, Sgouris JT, Schmidt PJ. Hepatitis B antigen (HB Ag) and antibody (anti-HB Ag) in cold ethanol fractions of human plasma.  Transfusion  1972;12;6  Link to Hepatitis B antigen (HB Ag) and antibody (anti-HB Ag) in cold ethanol fractions of human plasma.
  462. Journal Article Alter HJ, Holland PV, Purcell RH, Lander JJ, Feinstone SM, Morrow AG, Schmidt PJ. Posttransfusion hepatitis after exclusion of commercial and hepatitis-B antigen-positive donors.  Ann. Intern. Med.  1972;77;5  Link to Posttransfusion hepatitis after exclusion of commercial and hepatitis-B antigen-positive donors.
  463. Journal Article Holland PV, Purcell RH, Smith H, Alter HJ. Subtyping of hepatitis-associated antigen (HB-Ag); simplified technique with counterelectrophoresis.  J. Immunol.  1972;109;3  Link to Subtyping of hepatitis-associated antigen (HB-Ag); simplified technique with counterelectrophoresis.
  464. Journal Article Cherubin CE, Purcell RH, Lander JJ, McGinn TG, Cone LA. Acquisition of antibody to hepatitis B antigen in three socioeconomically different medical populations.  Lancet  1972;2;7769  Link to Acquisition of antibody to hepatitis B antigen in three socioeconomically different medical populations.
  465. Journal Article Maynard JE, Berquist KR, Krushak DH, Purcell RH. Experimental infection of chimpanzees with the virus of hepatitis B.  Nature  1972;237;5357  Link to Experimental infection of chimpanzees with the virus of hepatitis B.
  466. Journal Article Lander HJ, Holland PV, Alter HJ, Chanock RM, Purcell RH. Antibody to hepatitis-associated antigen. Frequency and pattern of response as detected by radioimmunoprecipitation.  JAMA  1972;220;8  Link to Antibody to hepatitis-associated antigen. Frequency and pattern of response as detected by radioimmunoprecipitation.
  467. Journal Article London WT, Alter HJ, Lander J, Purcell RH. Serial transmission in rhesus monkeys of an agent related to hepatitis-associated antigen.  J. Infect. Dis.  1972;125;4  Link to Serial transmission in rhesus monkeys of an agent related to hepatitis-associated antigen.
  468. 1971

  469. Journal Article Lander JJ, Giles JP, Purcell RH, Krugman S. Viral hepatitis, type B (MS-2 strain). Detection of antibody after primary infection.  N. Engl. J. Med.  1971;285;6  Link to Viral hepatitis, type B (MS-2 strain). Detection of antibody after primary infection.
  470. Comparative StudyJournal Article Alter HJ, Holland PV, Purcell RH. Counterelectrophoresis for detection of hepatitis--associated antigen: methodology and comparison with gel diffusion and complement fixation.  J. Lab. Clin. Med.  1971;77;6  Link to Counterelectrophoresis for detection of hepatitis--associated antigen: methodology and comparison with gel diffusion and complement fixation.
  471. Journal Article Gerin JL, Holland PV, Purcell RH. Australia antigen: large-scale purification from human serum and biochemical studies of its proteins.  J. Virol.  1971;7;5  Link to Australia antigen: large-scale purification from human serum and biochemical studies of its proteins.
  472. Journal Article Lander JJ, Alter HJ, Purcell RH. Frequency of antibody to hepatitis-associated antigen as measured by a new radioimmunoassay technique.  J. Immunol.  1971;106;5  Link to Frequency of antibody to hepatitis-associated antigen as measured by a new radioimmunoassay technique.
  473. Journal Article Purcell RH, Walsh JH, Holland PV, Morrow AG, Wood S, Chanock RM. Seroepidemiological studies of transfusion-associated hepatitis.  J. Infect. Dis.  1971;123;4  Link to Seroepidemiological studies of transfusion-associated hepatitis.
  474. 1970

  475. Journal Article Harwick HJ, Purcell RH, Iuppa JB, Fekety FR. Mycoplasma hominis and abortion.  J. Infect. Dis.  1970;121;3  Link to Mycoplasma hominis and abortion.
  476. Journal Article Purcell RH, Gerin JL, Holland PV, Cline WL, Chanock RM. Preparation and characterization of complement-fixing hepatitis-associated antigen and antiserum.  J. Infect. Dis.  1970;121;2  Link to Preparation and characterization of complement-fixing hepatitis-associated antigen and antiserum.
  477. Journal Article Walsh JH, Purcell RH, Morrow AG, Chanock RM, Schmidt PJ. Posttransfusion hepatitis after open-heart operations. Incidence after the administration of blood from commercial and volunteer donor populations.  JAMA  1970;211;2  Link to Posttransfusion hepatitis after open-heart operations. Incidence after the administration of blood from commercial and volunteer donor populations.
  478. 1969

  479. Journal Article Gerin JL, Purcell RH, Hoggan MD, Holland PV, Chanock RM. Biophysical properties of Australia antigen.  J. Virol.  1969;4;5  Link to Biophysical properties of Australia antigen.
  480. Journal Article Holland PV, Walsh JH, Morrow AG, Purcell RH. Failure of Australia antibody to prevent post-transfusion hepatitis.  Lancet  1969;2;7620  Link to Failure of Australia antibody to prevent post-transfusion hepatitis.
  481. Journal Article Purcell RH, Holland PV, Walsh JH, Wong DC, Morrow AG, Chanock RM. A complement-fixation test for measuring Australia antigen and antibody.  J. Infect. Dis.  1969;120;3  Link to A complement-fixation test for measuring Australia antigen and antibody.
  482. Journal Article Gerber P, Walsh JH, Rosenblum EN, Purcell RH. Association of EB-virus infection with the post-perfusion syndrome.  Lancet  1969;1;7595  Link to Association of EB-virus infection with the post-perfusion syndrome.
  483. 1967

  484. Journal Article Purcell RH, Wong D, Chanock RM, Taylor-Robinson D, Canchola J, Valdesuso J. Significance of antibody to mycoplasma as measured by metabolic-inhibition techniques.  Ann. N. Y. Acad. Sci.  1967;143;1  Link to Significance of antibody to mycoplasma as measured by metabolic-inhibition techniques.
  485. Journal Article Purcell RH, Chanock RM. Role of mycoplasmas in human respiratory disease.  Med. Clin. North Am.  1967;51;3  Link to Role of mycoplasmas in human respiratory disease.
  486. 1966

  487. Journal Article Smith CB, Purcell RH, Bellanti JA, Chanock RM. Protective effect of antibody to parainfluenza type 1 virus.  N. Engl. J. Med.  1966;275;21  Link to Protective effect of antibody to parainfluenza type 1 virus.
  488. Journal Article Taylor-Robinson D, Purcell RH. Mycoplasmas of the human urogenital tract and oropharynx and their possible role in disease: a review with some recent observations.  Proc. R. Soc. Med.  1966;59;11 Part 1  Link to Mycoplasmas of the human urogenital tract and oropharynx and their possible role in disease: a review with some recent observations.
  489. Journal Article Purcell RH, Somerson NL, Fox H, Wong DC, Turner HC, Chanock RM. Identification of acid-inducing agent and related mycoplasma as mycoplasma hyorhinis.  J. Natl. Cancer Inst.  1966;37;2  Link to Identification of acid-inducing agent and related mycoplasma as mycoplasma hyorhinis.
  490. In VitroJournal Article Purcell RH, Taylor-Robinson D, Wong DC, Chanock RM. A color test for the measurement of antibody to the non-acid-forming human Mycoplasma species.  Am. J. Epidemiol.  1966;84;1  Link to A color test for the measurement of antibody to the non-acid-forming human Mycoplasma species.
  491. Clinical TrialControlled Clinical TrialJournal Article Edmondson WP, Purcell RH, Gundelfinger BF, Love JW, Ludwig W, Chanock RM. Immunization by selective infection with type 4 adenovirus grown in human diploid tissue culture. II. specific protective effect against epidemic disease.  JAMA  1966;195;6  Link to Immunization by selective infection with type 4 adenovirus grown in human diploid tissue culture. II. specific protective effect against epidemic disease.
  492. 1965

  493. Journal Article Jensen KE, Senterfit LB, Chanock RM, Smith CB, Purcell RH. An inactivated mycoplasma pneumoniae vaccine.  JAMA  1965;194;3  Link to An inactivated mycoplasma pneumoniae vaccine.
  494. Journal Article MUFSON MA, LUDWIG WM, PURCELL RH, CATE TR, TAYLOR-ROBINSON D, CHANOCK RM. EXUDATIVE PHARYNGITIS FOLLOWING EXPERIMENTAL MYCOPLASMA HOMINIS: TYPE 1 INFECTION.  JAMA  1965;192  Link to EXUDATIVE PHARYNGITIS FOLLOWING EXPERIMENTAL MYCOPLASMA HOMINIS: TYPE 1 INFECTION.
  495. 1963

  496. Journal Article BONAR RA, PURCELL RH, BEARD D, BEARD JW. VIRUS OF AVIAN MYELOBLASTOSIS (BAI STRAIN A). XXIV. NUCLEOTIDE COMPOSITION OF THE PENTOSENUCLEIC ACID AND COMPARISON WITH STRAIN R (ERYTHROBLASTOSIS).  J. Natl. Cancer Inst.  1963;31  Link to VIRUS OF AVIAN MYELOBLASTOSIS (BAI STRAIN  A). XXIV. NUCLEOTIDE COMPOSITION OF THE PENTOSENUCLEIC ACID AND COMPARISON WITH STRAIN R (ERYTHROBLASTOSIS).
  497. 1962

  498. Journal Article PURCELL RH, BONAR RA, BEARD D, BEARD JW. Virus of avian myeloblastosis. XX. Amino acid composition.  J. Natl. Cancer Inst.  1962;28  Link to Virus of avian myeloblastosis. XX. Amino acid composition.
Back to page of Purcell, Robert H..

Due mainly to homonyms, errors are possible and if you detect "false positives" or "false negatives" don't be too frustrated and please contact the webmaster.